{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(20)"],"submitter":["Karai B"],"pubmed_abstract":["Multicolor flow cytometry (FC) evaluation has a key role in the diagnosis and prognostic stratification of ALL. Our aim was to create new analyzing protocols using multidimensional dot-plots. Seventy-two pediatric patients with ALL were included in this single-center study. Data of a normal BM sample and three BM samples of patients with BCP-ALL were merged, then all B cell populations of the four samples were presented in a single radar dot-plot, and those parameters and locations were selected in which the normal and pathological cell populations differed from each other the most. The integrated profile of immunophenotype resulted in a simple, rapid, and accurate method. There were no significant differences between the percentages of lymphoblasts in the detection of minimal residual dis"],"journal":["Cancers"],"pagination":["5044"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8533788"],"repository":["biostudies-literature"],"pubmed_title":["A Novel Method for the Evaluation of Bone Marrow Samples from Patients with Pediatric B-Cell Acute Lymphoblastic Leukemia-Multidimensional Flow Cytometry."],"pmcid":["PMC8533788"],"pubmed_authors":["Nagy AC","Tisza K","Eperjesi O","Kiss C","Kappelmayer J","Kelemen A","Karai B","Szegedi I","Ujfalusi A","Hevessy Z"],"additional_accession":[]},"is_claimable":false,"name":"A Novel Method for the Evaluation of Bone Marrow Samples from Patients with Pediatric B-Cell Acute Lymphoblastic Leukemia-Multidimensional Flow Cytometry.","description":"Multicolor flow cytometry (FC) evaluation has a key role in the diagnosis and prognostic stratification of ALL. Our aim was to create new analyzing protocols using multidimensional dot-plots. Seventy-two pediatric patients with ALL were included in this single-center study. Data of a normal BM sample and three BM samples of patients with BCP-ALL were merged, then all B cell populations of the four samples were presented in a single radar dot-plot, and those parameters and locations were selected in which the normal and pathological cell populations differed from each other the most. The integrated profile of immunophenotype resulted in a simple, rapid, and accurate method. There were no significant differences between the percentages of lymphoblasts in the detection of minimal residual dis","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-05T13:58:29.231Z","creation":"2025-04-05T13:58:29.231Z"},"accession":"S-EPMC8533788","cross_references":{"pubmed":["34680191"],"doi":["10.3390/cancers13205044"]}}