{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(10)"],"submitter":["Hoch M"],"pubmed_abstract":["Children have been disproportionately affected during the COVID-19 pandemic. We aimed to assess a saliva-based algorithm for SARS-CoV-2 testing to be used in schools and childcare institutions under pandemic conditions. A weekly SARS-CoV-2 sentinel study in primary schools, kindergartens, and childcare facilities was conducted over a 12-week-period. In a sub-study covering 7 weeks, 1895 paired oropharyngeal and saliva samples were processed for SARS-CoV-2 rRT-PCR testing in both asymptomatic children (n = 1243) and staff (n = 652). Forty-nine additional concurrent swab and saliva samples were collected from SARS-CoV-2 infected patients (patient cohort). The Salivette® system was used for saliva collection and assessed for feasibility and diagnostic performance. For children, a mean of 1.18"],"journal":["Diagnostics (Basel, Switzerland)"],"pagination":["1797"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8534592"],"repository":["biostudies-literature"],"pubmed_title":["Feasibility and Diagnostic Accuracy of Saliva-Based SARS-CoV-2 Screening in Educational Settings and Children Aged <12 Years."],"pmcid":["PMC8534592"],"pubmed_authors":["von Both U","Ackermann N","Kolberg L","Gruenthaler V","Fingerle V","Meyer-Buehn M","Schober T","Rack-Hoch A","Sing A","Huebner J","Vogel S","Liebl B","Kuttiadan S","Hoch M","Eberle U"],"additional_accession":[]},"is_claimable":false,"name":"Feasibility and Diagnostic Accuracy of Saliva-Based SARS-CoV-2 Screening in Educational Settings and Children Aged <12 Years.","description":"Children have been disproportionately affected during the COVID-19 pandemic. We aimed to assess a saliva-based algorithm for SARS-CoV-2 testing to be used in schools and childcare institutions under pandemic conditions. A weekly SARS-CoV-2 sentinel study in primary schools, kindergartens, and childcare facilities was conducted over a 12-week-period. In a sub-study covering 7 weeks, 1895 paired oropharyngeal and saliva samples were processed for SARS-CoV-2 rRT-PCR testing in both asymptomatic children (n = 1243) and staff (n = 652). Forty-nine additional concurrent swab and saliva samples were collected from SARS-CoV-2 infected patients (patient cohort). The Salivette® system was used for saliva collection and assessed for feasibility and diagnostic performance. For children, a mean of 1.18","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-20T02:04:32.727Z","creation":"2025-04-20T02:04:32.727Z"},"accession":"S-EPMC8534592","cross_references":{"pubmed":["34679495"],"doi":["10.3390/diagnostics11101797"]}}