{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yu X"],"funding":["Strategic Collaborative Innovation Team","National Natural Science Funds of China","Shanghai Three-year Action Plan for Public Health under Grant"],"pagination":["10980"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8535751"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(20)"],"pubmed_abstract":["<h4>Background</h4>Ensuring adherence guarantees the efficacy of pre-exposure prophylaxis (PrEP).<h4>Methods</h4>We conducted a cross-sectional study among 816 sexually transmitted infection (STI) patients in Shanghai. The questionnaire included self-reported demographic characteristics, self-administered items on adherence to free oral PrEP, and PrEP uptake behavior measurement. We conducted item analysis, reliability analysis, validity analysis and receiver operating characteristic (ROC) curve analysis.<h4>Results</h4>Not all items were considered acceptable in the item analysis. The questionnaire had a McDonald's ω coefficient of 0.847. The scale-level content validity index (CVI) was 0.938 and the item-level CVI of each item ranged from 0.750 to 1. In exploratory factor analysis, we introduced a four-factor model accounting for 79.838% of the aggregate variance, which was validated in confirmatory factor analysis. Adding PrEP adherence questionnaire scores contributed to prediction of PrEP uptake behavior (<i>p</i> < 0.001) in regression analysis. The maximum area under the ROC curve was 0.778 (95% IC: 0.739-0.817).<h4>Conclusion</h4>The PrEP adherence questionnaire presented psychometric validation among STI patients."],"journal":["International journal of environmental research and public health"],"pubmed_title":["Pre-Exposure Prophylaxis (PrEP) Adherence Questionnaire: Psychometric Validation among Sexually Transmitted Infection Patients in China."],"pmcid":["PMC8535751"],"funding_grant_id":["SSMU-ZLCX20180601)","71603166, 71673187","GWV-10.2-XD13, GWV-10.1-XK15, GWV-10.1-XK18"],"pubmed_authors":["Ni Y","Chang R","Gong R","Wang S","Xu C","Cai Y","Wang H","Wang Y","Yu X"],"additional_accession":[]},"is_claimable":false,"name":"Pre-Exposure Prophylaxis (PrEP) Adherence Questionnaire: Psychometric Validation among Sexually Transmitted Infection Patients in China.","description":"<h4>Background</h4>Ensuring adherence guarantees the efficacy of pre-exposure prophylaxis (PrEP).<h4>Methods</h4>We conducted a cross-sectional study among 816 sexually transmitted infection (STI) patients in Shanghai. The questionnaire included self-reported demographic characteristics, self-administered items on adherence to free oral PrEP, and PrEP uptake behavior measurement. We conducted item analysis, reliability analysis, validity analysis and receiver operating characteristic (ROC) curve analysis.<h4>Results</h4>Not all items were considered acceptable in the item analysis. The questionnaire had a McDonald's ω coefficient of 0.847. The scale-level content validity index (CVI) was 0.938 and the item-level CVI of each item ranged from 0.750 to 1. In exploratory factor analysis, we introduced a four-factor model accounting for 79.838% of the aggregate variance, which was validated in confirmatory factor analysis. Adding PrEP adherence questionnaire scores contributed to prediction of PrEP uptake behavior (<i>p</i> < 0.001) in regression analysis. The maximum area under the ROC curve was 0.778 (95% IC: 0.739-0.817).<h4>Conclusion</h4>The PrEP adherence questionnaire presented psychometric validation among STI patients.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2026-07-09T11:58:19.222Z","creation":"2025-04-07T02:26:10.424Z"},"accession":"S-EPMC8535751","cross_references":{"pubmed":["34682730"],"doi":["10.3390/ijerph182010980"]}}