biostudies-literatureMoheet IAMinistry of Higher Education3504https://www.ebi.ac.uk/biostudies/studies/S-EPMC8537145biostudies-literatureUnknown13(20)One of the foremost missions in restorative dentistry is to discover a suitable material that can substitute lost and damaged tooth structure. To this date, most of the restorative materials utilized in dentistry are bio-inert. It is predicted that the addition of nano-HA-SiO2 to GIC matrix could produce a material with better ion-exchange between the restorative material and natural teeth. Therefore, the aim of the current study was to synthesize and investigate the transfer of specific elements (calcium, phosphorus, fluoride, silica, strontium, and alumina) between nano-hydroxyapatite-silica added GIC (nano-HA-SiO2-GIC) and human enamel and dentine. The novel nano-hydroxyapatite-silica (nano-HA-SiO2) was synthesized using one-pot sol-gel method and added to cGIC. Semi-quantitative energyPolymersAnalysis of Ionic-Exchange of Selected Elements between Novel Nano-Hydroxyapatite-Silica Added Glass Ionomer Cement and Natural Teeth.PMC8537145FRGS/203/PPSG/6171173Masudi SMKannan TPLuddin NAb Rahman IMoheet IANik Abd Ghani NRfalseAnalysis of Ionic-Exchange of Selected Elements between Novel Nano-Hydroxyapatite-Silica Added Glass Ionomer Cement and Natural Teeth.One of the foremost missions in restorative dentistry is to discover a suitable material that can substitute lost and damaged tooth structure. To this date, most of the restorative materials utilized in dentistry are bio-inert. It is predicted that the addition of nano-HA-SiO2 to GIC matrix could produce a material with better ion-exchange between the restorative material and natural teeth. Therefore, the aim of the current study was to synthesize and investigate the transfer of specific elements (calcium, phosphorus, fluoride, silica, strontium, and alumina) between nano-hydroxyapatite-silica added GIC (nano-HA-SiO2-GIC) and human enamel and dentine. The novel nano-hydroxyapatite-silica (nano-HA-SiO2) was synthesized using one-pot sol-gel method and added to cGIC. Semi-quantitative energy2021-01-01T00:00:00Z2021 Oct2025-04-22T11:31:29.997Z2025-04-05T23:59:21.674ZS-EPMC85371453468526310.3390/polym13203504