{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["26(20)"],"submitter":["Zeliszewska P"],"pubmed_abstract":["The deposition kinetics of polymer particles with fibrinogen molecule coronas at bare and poly-L-lysine (PLL) modified mica was studied using the microfluid impinging-jet cell. Basic physicochemical characteristics of fibrinogen and the particles were acquired using dynamic light scattering and the electrophoretic mobility methods, whereas the zeta potential of the substrates was determined using streaming potential measurements. Subsequently, an efficient method for the preparation of the particles with coronas, characterized by a controlled fibrinogen coverage, was developed. This enabled us to carry out measurements, which confirmed that the deposition kinetics of the particles at mica vanished at pH above 5. In contrast, the particle deposition of PLL modified mica was at maximum for p"],"journal":["Molecules (Basel, Switzerland)"],"pagination":["6299"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8538388"],"repository":["biostudies-literature"],"pubmed_title":["Deposition of Polymer Particles with Fibrinogen Corona at Abiotic Surfaces under Flow Conditions."],"pmcid":["PMC8538388"],"pubmed_authors":["Zeliszewska P","Wasilewska M","Ciesla M","Adamczyk Z"],"additional_accession":[]},"is_claimable":false,"name":"Deposition of Polymer Particles with Fibrinogen Corona at Abiotic Surfaces under Flow Conditions.","description":"The deposition kinetics of polymer particles with fibrinogen molecule coronas at bare and poly-L-lysine (PLL) modified mica was studied using the microfluid impinging-jet cell. Basic physicochemical characteristics of fibrinogen and the particles were acquired using dynamic light scattering and the electrophoretic mobility methods, whereas the zeta potential of the substrates was determined using streaming potential measurements. Subsequently, an efficient method for the preparation of the particles with coronas, characterized by a controlled fibrinogen coverage, was developed. This enabled us to carry out measurements, which confirmed that the deposition kinetics of the particles at mica vanished at pH above 5. In contrast, the particle deposition of PLL modified mica was at maximum for p","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-21T22:01:07.052Z","creation":"2025-04-21T22:01:07.052Z"},"accession":"S-EPMC8538388","cross_references":{"pubmed":["34684880"],"doi":["10.3390/molecules26206299"]}}