biostudies-literatureUnknown13(10)Guz Mark A<h4>Background</h4>Long-term parenteral nutrition (PN) has been associated with renal complications, including hypercalciuria, nephrocalcinosis, proteinuria and reduced glomerular filtration rate (GFR). Pediatric data are scarce and mostly short-term. Our study aimed to evaluate renal complications in children with intestinal failure (IF) receiving long-term PN.<h4>Methods</h4>A cross-sectional study was performed in a tertiary pediatric IF clinic of patients receiving home-PN treatment for more than 1 year. Data regarding medical background, anthropometrics, laboratory investigations and abdominal sonography were retrieved.<h4>Results</h4>Complete data were available for 15 children (67% males), with a median age of 6 (range 1.5-15) years and a median (IQR) PN duration of 4 (1.5-6) years.Nutrients3647https://www.ebi.ac.uk/biostudies/studies/S-EPMC8539167biostudies-literatureChildren with Intestinal Failure Maintain Their Renal Function on Long-Term Parenteral Nutrition.PMC8539167Marderfeld LLevi SDavidovits MShamir RGuz Mark AfalseChildren with Intestinal Failure Maintain Their Renal Function on Long-Term Parenteral Nutrition.<h4>Background</h4>Long-term parenteral nutrition (PN) has been associated with renal complications, including hypercalciuria, nephrocalcinosis, proteinuria and reduced glomerular filtration rate (GFR). Pediatric data are scarce and mostly short-term. Our study aimed to evaluate renal complications in children with intestinal failure (IF) receiving long-term PN.<h4>Methods</h4>A cross-sectional study was performed in a tertiary pediatric IF clinic of patients receiving home-PN treatment for more than 1 year. Data regarding medical background, anthropometrics, laboratory investigations and abdominal sonography were retrieved.<h4>Results</h4>Complete data were available for 15 children (67% males), with a median age of 6 (range 1.5-15) years and a median (IQR) PN duration of 4 (1.5-6) years.2021-01-01T00:00:00Z2021 Oct2026-07-11T03:20:43.624Z2025-04-05T13:58:07.918ZS-EPMC85391673468464710.3390/nu13103647