biostudies-literatureRyan CTNHLBI NIH HHSNational Heart, Lung, and Blood InstituteSociety of Thoracic SurgeonsNational Institutes of Health763-772https://www.ebi.ac.uk/biostudies/studies/S-EPMC8542644biostudies-literatureUnknown113(3)<h4>Background</h4>This study evaluated outcomes and risk factors for surgical aortic valve replacement (SAVR) for aortic insufficiency (AI) in a national cohort. We analyzed the incidence, outcomes, and risk factors for SAVR for AI in the Society of Thoracic Surgeons Adult Cardiac Surgery Database.<h4>Methods</h4>The national database was queried for patients with moderate or greater AI undergoing isolated SAVR between July 2011 and December 2018. Patients with moderate or greater aortic stenosis, acute dissection, active endocarditis, concomitant procedures, or emergent operation were excluded. AI was staged using guideline criteria based on symptoms and ventricular remodeling. Operative mortality and morbidity were compared between stages, and risk factors for operative death were identThe Annals of thoracic surgeryOutcomes of Aortic Valve Replacement for Chronic Aortic Insufficiency: Analysis of the Society of Thoracic Surgeons Database.PMC85426441R01HL152280-01T32-HL139430R01 HL152280T32 HL139430Amos CICoselli JSAlmousa AZea-Vera RGhanta RKZhang QRosengart TKRyan CTfalseOutcomes of Aortic Valve Replacement for Chronic Aortic Insufficiency: Analysis of the Society of Thoracic Surgeons Database.<h4>Background</h4>This study evaluated outcomes and risk factors for surgical aortic valve replacement (SAVR) for aortic insufficiency (AI) in a national cohort. We analyzed the incidence, outcomes, and risk factors for SAVR for AI in the Society of Thoracic Surgeons Adult Cardiac Surgery Database.<h4>Methods</h4>The national database was queried for patients with moderate or greater AI undergoing isolated SAVR between July 2011 and December 2018. Patients with moderate or greater aortic stenosis, acute dissection, active endocarditis, concomitant procedures, or emergent operation were excluded. AI was staged using guideline criteria based on symptoms and ventricular remodeling. Operative mortality and morbidity were compared between stages, and risk factors for operative death were ident2022-01-01T00:00:00Z2022 Mar2025-04-04T13:40:32.745Z2025-04-04T13:40:32.745ZS-EPMC85426443391005010.1016/j.athoracsur.2021.04.027