{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vyas A"],"funding":["University of Rhode Island Foundation","National Institute of General Medical Sciences","NIGMS NIH HHS"],"pagination":["1092-1099"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8544754"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(7)"],"pubmed_abstract":["<h4>Purpose</h4>We examined guideline-concordant initial systemic treatment among women with metastatic breast cancer, its predictors, and if guideline-concordant treatment was associated with mortality, healthcare utilization and Medicare expenditures.<h4>Methods</h4>This retrospective observational cohort study was conducted using the Surveillance, Epidemiology, End Results-Medicare linked database. Women aged 66-90 years diagnosed with metastatic breast cancer during 2010-2013 (N = 1282) were included. The National Comprehensive Cancer Network treatment guidelines were used to determine the guideline-concordant initial systemic treatment following cancer diagnosis. A logistic regression analysis was conducted to examine significant predictors of guideline-concordant treatment. Generaliz"],"journal":["Journal of geriatric oncology"],"pubmed_title":["Association of guideline-concordant initial systemic treatment with clinical and economic outcomes among older women with metastatic breast cancer in the United States."],"pmcid":["PMC8544754"],"funding_grant_id":["U54 GM115677","P20 GM125507"],"pubmed_authors":["Vyas A","Mantaian T","Kamat S","Kogut S","Kurian S"],"additional_accession":[]},"is_claimable":false,"name":"Association of guideline-concordant initial systemic treatment with clinical and economic outcomes among older women with metastatic breast cancer in the United States.","description":"<h4>Purpose</h4>We examined guideline-concordant initial systemic treatment among women with metastatic breast cancer, its predictors, and if guideline-concordant treatment was associated with mortality, healthcare utilization and Medicare expenditures.<h4>Methods</h4>This retrospective observational cohort study was conducted using the Surveillance, Epidemiology, End Results-Medicare linked database. Women aged 66-90 years diagnosed with metastatic breast cancer during 2010-2013 (N = 1282) were included. The National Comprehensive Cancer Network treatment guidelines were used to determine the guideline-concordant initial systemic treatment following cancer diagnosis. A logistic regression analysis was conducted to examine significant predictors of guideline-concordant treatment. Generaliz","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-04T09:37:13.255Z","creation":"2025-04-04T09:37:13.255Z"},"accession":"S-EPMC8544754","cross_references":{"pubmed":["34099411"],"doi":["10.1016/j.jgo.2021.05.012"]}}