{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["156(12)"],"submitter":["Gertsen EC"],"pubmed_abstract":["<h4>Importance</h4>The optimal staging for gastric cancer remains a matter of debate.<h4>Objective</h4>To evaluate the value of 18F-fludeoxyglucose-positron emission tomography with computed tomography (FDG-PET/CT) and staging laparoscopy (SL) in addition to initial staging by means of gastroscopy and CT in patients with locally advanced gastric cancer.<h4>Design, setting, and participants</h4>This multicenter prospective, observational cohort study included 394 patients with locally advanced, clinically curable gastric adenocarcinoma (≥cT3 and/or N+, M0 category based on CT) between August 1, 2017, and February 1, 2020.<h4>Exposures</h4>All patients underwent an FDG-PET/CT and/or SL in addition to initial staging.<h4>Main outcomes and measures</h4>The primary outcome was the number of pat"],"journal":["JAMA surgery"],"pagination":["e215340"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8552113"],"repository":["biostudies-literature"],"pubmed_title":["18F-Fludeoxyglucose-Positron Emission Tomography/Computed Tomography and Laparoscopy for Staging of Locally Advanced Gastric Cancer: A Multicenter Prospective Dutch Cohort Study (PLASTIC)."],"pmcid":["PMC8552113"],"pubmed_authors":["Daams F","Bouwmeester E","Profar J","Wessels FJ","Tummers S","Pierie JP","Siersema PD","de Mooij K","van Hillegersberg R","van Det MJ","van Laarhoven HWM","Hartgrink HH","Vegt E","Eker HH","Heisterkamp J","Heijmans M","Pijpers J","Luyer MDP","Masselink I","Wevers KP","van Kleef JJ","van den Berg JW","van Dam M","van Duijvendijk P","van der Peet DL","Frederix GWJ","van Berge Henegouwen MI","Hol L","van Groenestyn A","Spillenaar Bilgen EJ","Nieuwenhuijzen GAP","Thijssen AY","Brenkman HJF","Kouwenhoven EA","van Grieken NCT","de Steur WO","Gisbertz SS","Wijnhoven BPL","Ruurda JP","van Etten B","Prins M","Gertsen EC","van Lanschot JJB","Hulsewe KWE","Lagarde SM","PLASTIC Study Group","Wassenaar E","de Vries N","Haj Mohammad N","van der Meulen MP","Beumer D","van Sandick JW","Belt EJT","Stoot JHMB"],"additional_accession":[]},"is_claimable":false,"name":"18F-Fludeoxyglucose-Positron Emission Tomography/Computed Tomography and Laparoscopy for Staging of Locally Advanced Gastric Cancer: A Multicenter Prospective Dutch Cohort Study (PLASTIC).","description":"<h4>Importance</h4>The optimal staging for gastric cancer remains a matter of debate.<h4>Objective</h4>To evaluate the value of 18F-fludeoxyglucose-positron emission tomography with computed tomography (FDG-PET/CT) and staging laparoscopy (SL) in addition to initial staging by means of gastroscopy and CT in patients with locally advanced gastric cancer.<h4>Design, setting, and participants</h4>This multicenter prospective, observational cohort study included 394 patients with locally advanced, clinically curable gastric adenocarcinoma (≥cT3 and/or N+, M0 category based on CT) between August 1, 2017, and February 1, 2020.<h4>Exposures</h4>All patients underwent an FDG-PET/CT and/or SL in addition to initial staging.<h4>Main outcomes and measures</h4>The primary outcome was the number of pat","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-26T10:42:14.794Z","creation":"2025-04-06T13:27:55.108Z"},"accession":"S-EPMC8552113","cross_references":{"pubmed":["34705049"],"doi":["10.1001/jamasurg.2021.5340"]}}