biostudies-literatureUnknown116(11)Nagata N<h4>Introduction</h4>The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy is a risk-stratifying tool to identify etiology and predict outcomes and whether presenting symptoms can differentiate the etiologies in patients with hematochezia.<h4>Methods</h4>This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 patients admitted for outpatient-onset acute hematochezia.<h4>Results</h4>Patients were mostly elderly population, and 29.5% had hemodynamic instability. Computed tomography was performed in 69.1% and colonoscopy in 87.7%. Diagnostic yield of colonoscopy reached 94.9%, most frequently diverticular bleeding. Thirty-day rebleeding rates were significantly higher with diverticuloThe American journal of gastroenterology2222-2234https://www.ebi.ac.uk/biostudies/studies/S-EPMC8560163biostudies-literatureIdentifying Bleeding Etiologies by Endoscopy Affected Outcomes in 10,342 Cases With Hematochezia: CODE BLUE-J Study.PMC8560163Kinjo KFujii HMizukami KFukuzawa MKinjo TOmori JMizuki AGunji NNarasaka TKobayashi KKinjo YYamada AIkeya TAoyama TWatanabe KMiki KFunakoshi SNarimatsu KSumida YManabe NKawai TMikami TKawagishi KFunabiki TMatsuhashi TKiyotoki STominaga NUotani TSuzuki SKaise MUemura NSato YMurata MNagata NFujimori SFujita MIshii NHayasaka JKishino TNagaike KTakao AGushima RFuyuno YYamauchi AItoi TToya YKomaki YSawada TSato HfalseIdentifying Bleeding Etiologies by Endoscopy Affected Outcomes in 10,342 Cases With Hematochezia: CODE BLUE-J Study.<h4>Introduction</h4>The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy is a risk-stratifying tool to identify etiology and predict outcomes and whether presenting symptoms can differentiate the etiologies in patients with hematochezia.<h4>Methods</h4>This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 patients admitted for outpatient-onset acute hematochezia.<h4>Results</h4>Patients were mostly elderly population, and 29.5% had hemodynamic instability. Computed tomography was performed in 69.1% and colonoscopy in 87.7%. Diagnostic yield of colonoscopy reached 94.9%, most frequently diverticular bleeding. Thirty-day rebleeding rates were significantly higher with diverticulo2021-01-01T00:00:00Z2021 Nov2025-04-04T19:55:25.765Z2022-02-11T12:32:17.349ZS-EPMC85601633438814010.14309/ajg.0000000000001413