{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Giugni A"],"funding":["FP7 Health"],"pagination":["158"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8561979"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(1)"],"pubmed_abstract":["<h4>Background</h4>We leveraged the data of the international CREACTIVE consortium to investigate whether the outcome of traumatic brain injury (TBI) patients admitted to intensive care units (ICU) in hospitals without on-site neurosurgical capabilities (no-NSH) would differ had the same patients been admitted to ICUs in hospitals with neurosurgical capabilities (NSH).<h4>Methods</h4>The CREACTIVE observational study enrolled more than 8000 patients from 83 ICUs. Adult TBI patients admitted to no-NSH ICUs within 48 h of trauma were propensity-score matched 1:3 with patients admitted to NSH ICUs. The primary outcome was the 6-month extended Glasgow Outcome Scale (GOS-E), while secondary outcomes were ICU and hospital mortality.<h4>Results</h4>A total of 232 patients, less than 5% of the eli"],"journal":["Scandinavian journal of trauma, resuscitation and emergency medicine"],"pubmed_title":["Hospitals with and without neurosurgery: a comparative study evaluating the outcome of patients with traumatic brain injury."],"pmcid":["PMC8561979"],"funding_grant_id":["602714"],"pubmed_authors":["Ciceri R","Terzitta M","Pellicioli I","Montis A","Kapias M","Antiga L","Martino C","Lagomarsino S","Gyulai R","Parrini V","Ruggeri P","Nardai G","Martelli M","Novak Jankovic V","Kasnik D","Poole D","Bert PP","Carrara G","Duek O","Zompanti V","Vecchiarelli A","Piva S","Calicchio G","Rosano A","Melis M","Karadzic D","Agnes S","Duda I","Bertolini G","Robak P","Ferri E","Natalini G","Tinturini R","Dessena MG","Fagoni N","Bekos V","Hadash A","Mizak W","Lamborghini S","Giugni A","Skoti M","Bottazzi A","Rekas A","Sulkowski W","Martin MA","Gamberini L","Curto F","Malacarne P","Zoppellari R","Nemes C","CREACTIVE consortium","Agostini F","Kaps R","Visconti S","Bako BE","Gamberini E","De Cristofaro A","Petrucci N","Casagli S","Buldini V","Szaszi AK","Cocciolo F","Kioulpalis A","Kyriakides E","Csomos A","Szedlak B","Tofani R","Ajmone-Cat C","Xirouchaki N","Carlin F","Jurekovic V","Paci G","Bassi G","Kompan J","De Luca A","Bonato A","Mikaszewska-Sokolewicz M","Calamai I","Dabrowski W","Partala P","Gradisek P","Mirkovic T","Munari M","Nattino G","Pastorelli M","Castioni CA","Spagarino E","Ilia S","Pagani M","Cseplo P","Bernasconi MO","Marudi A","Kyprianou T","Giuntini R","Bocci MG","Radrizzani D","Livigni S","Fassini P","Lazar I","Gattari D","Jereb M","Nascimben E","Tselioti P","Skrt A","Guido S","Brissy O","Bellin M","Mengoli F","Sacchi M","Venturini E","Portolani L","Filekovic S","Bonato V","Fleming JM","Fiore G","Negro G","Bonizzoli M","Bonucci P","Chieregato A","Crestan E","Hribar R","Gianni M"],"additional_accession":[]},"is_claimable":false,"name":"Hospitals with and without neurosurgery: a comparative study evaluating the outcome of patients with traumatic brain injury.","description":"<h4>Background</h4>We leveraged the data of the international CREACTIVE consortium to investigate whether the outcome of traumatic brain injury (TBI) patients admitted to intensive care units (ICU) in hospitals without on-site neurosurgical capabilities (no-NSH) would differ had the same patients been admitted to ICUs in hospitals with neurosurgical capabilities (NSH).<h4>Methods</h4>The CREACTIVE observational study enrolled more than 8000 patients from 83 ICUs. Adult TBI patients admitted to no-NSH ICUs within 48 h of trauma were propensity-score matched 1:3 with patients admitted to NSH ICUs. The primary outcome was the 6-month extended Glasgow Outcome Scale (GOS-E), while secondary outcomes were ICU and hospital mortality.<h4>Results</h4>A total of 232 patients, less than 5% of the eli","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2026-05-08T12:14:52.838Z","creation":"2022-02-11T12:32:27.887Z"},"accession":"S-EPMC8561979","cross_references":{"pubmed":["34727955"],"doi":["10.1186/s13049-021-00959-2"]}}