biostudies-literatureGiugni AFP7 Health158https://www.ebi.ac.uk/biostudies/studies/S-EPMC8561979biostudies-literatureUnknown29(1)<h4>Background</h4>We leveraged the data of the international CREACTIVE consortium to investigate whether the outcome of traumatic brain injury (TBI) patients admitted to intensive care units (ICU) in hospitals without on-site neurosurgical capabilities (no-NSH) would differ had the same patients been admitted to ICUs in hospitals with neurosurgical capabilities (NSH).<h4>Methods</h4>The CREACTIVE observational study enrolled more than 8000 patients from 83 ICUs. Adult TBI patients admitted to no-NSH ICUs within 48 h of trauma were propensity-score matched 1:3 with patients admitted to NSH ICUs. The primary outcome was the 6-month extended Glasgow Outcome Scale (GOS-E), while secondary outcomes were ICU and hospital mortality.<h4>Results</h4>A total of 232 patients, less than 5% of the eliScandinavian journal of trauma, resuscitation and emergency medicineHospitals with and without neurosurgery: a comparative study evaluating the outcome of patients with traumatic brain injury.PMC8561979602714Ciceri RTerzitta MPellicioli IMontis AKapias MAntiga LMartino CLagomarsino SGyulai RParrini VRuggeri PNardai GMartelli MNovak Jankovic VKasnik DPoole DBert PPCarrara GDuek OZompanti VVecchiarelli APiva SCalicchio GRosano AMelis MKaradzic DAgnes SDuda IBertolini GRobak PFerri ENatalini GTinturini RDessena MGFagoni NBekos VHadash AMizak WLamborghini SGiugni ASkoti MBottazzi ARekas ASulkowski WMartin MAGamberini LCurto FMalacarne PZoppellari RNemes CCREACTIVE consortiumAgostini FKaps RVisconti SBako BEGamberini EDe Cristofaro APetrucci NCasagli SBuldini VSzaszi AKCocciolo FKioulpalis AKyriakides ECsomos ASzedlak BTofani RAjmone-Cat CXirouchaki NCarlin FJurekovic VPaci GBassi GKompan JDe Luca ABonato AMikaszewska-Sokolewicz MCalamai IDabrowski WPartala PGradisek PMirkovic TMunari MNattino GPastorelli MCastioni CASpagarino EIlia SPagani MCseplo PBernasconi MOMarudi AKyprianou TGiuntini RBocci MGRadrizzani DLivigni SFassini PLazar IGattari DJereb MNascimben ETselioti PSkrt AGuido SBrissy OBellin MMengoli FSacchi MVenturini EPortolani LFilekovic SBonato VFleming JMFiore GNegro GBonizzoli MBonucci PChieregato ACrestan EHribar RGianni MfalseHospitals with and without neurosurgery: a comparative study evaluating the outcome of patients with traumatic brain injury.<h4>Background</h4>We leveraged the data of the international CREACTIVE consortium to investigate whether the outcome of traumatic brain injury (TBI) patients admitted to intensive care units (ICU) in hospitals without on-site neurosurgical capabilities (no-NSH) would differ had the same patients been admitted to ICUs in hospitals with neurosurgical capabilities (NSH).<h4>Methods</h4>The CREACTIVE observational study enrolled more than 8000 patients from 83 ICUs. Adult TBI patients admitted to no-NSH ICUs within 48 h of trauma were propensity-score matched 1:3 with patients admitted to NSH ICUs. The primary outcome was the 6-month extended Glasgow Outcome Scale (GOS-E), while secondary outcomes were ICU and hospital mortality.<h4>Results</h4>A total of 232 patients, less than 5% of the eli2021-01-01T00:00:00Z2021 Nov2026-05-08T12:14:52.838Z2022-02-11T12:32:27.887ZS-EPMC85619793472795510.1186/s13049-021-00959-2