biostudies-literatureUnknown12Wallner AAgence Nationale de la RechercheConsortium of International Agricultural Research CentersMinistère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche<i>Burkholderia sensu lato</i> species are prominent for their diversity of hosts. The type 3 secretion system (T3SS) is a major mechanism impacting the interactions between bacteria and eukaryotic hosts. Besides the human pathogenic species <i>Burkholderia pseudomallei</i> and closely affiliated species, the T3SS has received little attention in this genus as in taxonomically and evolutionary close genera <i>Paraburkholderia</i>, <i>Caballeronia</i>, <i>Trinickia</i>, and <i>Mycetohabitans</i>. We proceeded to identify and characterize the diversity of T3SS types using the genomic data from a subset of 145 strains representative of the species diversity found in the <i>Burkholderia s.l.</i> group. Through an analysis of their phylogenetic distribution, we identified two new T3SS types witFrontiers in microbiology761215https://www.ebi.ac.uk/biostudies/studies/S-EPMC8565462biostudies-literatureGenetic Diversity of Type 3 Secretion System in <i>Burkholderia s.l.</i> and Links With Plant Host Adaptation.PMC8565462Moulin LRimbault IBusset NWallner ABena GfalseGenetic Diversity of Type 3 Secretion System in <i>Burkholderia s.l.</i> and Links With Plant Host Adaptation.<i>Burkholderia sensu lato</i> species are prominent for their diversity of hosts. The type 3 secretion system (T3SS) is a major mechanism impacting the interactions between bacteria and eukaryotic hosts. Besides the human pathogenic species <i>Burkholderia pseudomallei</i> and closely affiliated species, the T3SS has received little attention in this genus as in taxonomically and evolutionary close genera <i>Paraburkholderia</i>, <i>Caballeronia</i>, <i>Trinickia</i>, and <i>Mycetohabitans</i>. We proceeded to identify and characterize the diversity of T3SS types using the genomic data from a subset of 145 strains representative of the species diversity found in the <i>Burkholderia s.l.</i> group. Through an analysis of their phylogenetic distribution, we identified two new T3SS types wit2021-01-01T00:00:00Z20212026-05-09T01:49:36.428Z2022-02-11T12:42:27.314ZS-EPMC85654623474507010.3389/fmicb.2021.761215