biostudies-literatureDewey MIntramural NIH HHSCanon Medical Systems Corporation Tokyo CL SquareNational Heart, Lung, and Blood InstituteNational Institutes of Health485-491https://www.ebi.ac.uk/biostudies/studies/S-EPMC8570979biostudies-literatureUnknown15(6)<h4>Background</h4>Few data exist on long-term outcome in patients undergoing combined coronary CT angiography (CTA) and myocardial CT perfusion imaging (CTP) as well as invasive coronary angiography (ICA) and single photon emission tomography (SPECT).<h4>Methods</h4>At 16 centers, 381 patients were followed for major adverse cardiac events (MACE) for the CORE320 study. All patients underwent coronary CTA, CTP, and SPECT before ICA within 60 days. Prognostic performance according binary results (normal/abnormal) was assessed by 5-year major cardiovascular events (MACE) free survival and area under the receiver-operating-characteristic curve (AUC).<h4>Results</h4>Follow up beyond 2-years was available in 323 patients. MACE-free survival rate was greater among patients with normal combined CJournal of cardiovascular computed tomographyPrognostic value of noninvasive combined anatomic/functional assessment by cardiac CT in patients with suspected coronary artery disease - Comparison with invasive coronary angiography and nuclear myocardial perfusion imaging for the five-year-follow up of the CORE320 multicenter study.PMC8570979ZIA HL006138ZIA HL006220Ostovaneh MRVavere ALGeorge RTTan SYPaul NCerci RNiinuma HNomura CLima JACKitagawa KLaham RDi Carli MMatheson MBRochitte CEHoe JChen MYLaule MJinzaki MArbab-Zadeh ADewey MCox CSakuma HYoshioka KBrinker JArai AEKofoed KClouse MEKuribayashi SScholte AJMehra VCRybicki FJMiller JMfalsePrognostic value of noninvasive combined anatomic/functional assessment by cardiac CT in patients with suspected coronary artery disease - Comparison with invasive coronary angiography and nuclear myocardial perfusion imaging for the five-year-follow up of the CORE320 multicenter study.<h4>Background</h4>Few data exist on long-term outcome in patients undergoing combined coronary CT angiography (CTA) and myocardial CT perfusion imaging (CTP) as well as invasive coronary angiography (ICA) and single photon emission tomography (SPECT).<h4>Methods</h4>At 16 centers, 381 patients were followed for major adverse cardiac events (MACE) for the CORE320 study. All patients underwent coronary CTA, CTP, and SPECT before ICA within 60 days. Prognostic performance according binary results (normal/abnormal) was assessed by 5-year major cardiovascular events (MACE) free survival and area under the receiver-operating-characteristic curve (AUC).<h4>Results</h4>Follow up beyond 2-years was available in 323 patients. MACE-free survival rate was greater among patients with normal combined C2021-01-01T00:00:00Z2021 Nov-Dec2025-04-04T22:33:42.176Z2025-02-19T03:23:57.897ZS-EPMC85709793402475710.1016/j.jcct.2021.04.005