{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(11)"],"submitter":["Crispi F"],"pubmed_abstract":["<h4>Importance</h4>Being born small for gestational age (SGA), approximately 10% of all births, is associated with increased risk of cardiovascular mortality in adulthood, but mechanistic pathways are unclear. Cardiac remodeling and dysfunction occur in fetuses SGA and children born SGA, but it is uncertain whether and how these changes persist into adulthood.<h4>Objective</h4>To evaluate baseline cardiac function and structure and exercise capacity in young adults born SGA.<h4>Design, setting, and participants</h4>This cohort study conducted from January 2015 to January 2018 assessed a perinatal cohort born at a tertiary university hospital in Spain between 1975 and 1995. Participants included 158 randomly selected young adults aged 20 to 40 years born SGA (birth weight below the 10th cen"],"journal":["JAMA cardiology"],"pagination":["1308-1316"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8576583"],"repository":["biostudies-literature"],"pubmed_title":["Exercise Capacity in Young Adults Born Small for Gestational Age."],"pmcid":["PMC8576583"],"pubmed_authors":["Crovetto F","Gratacos E","Rodriguez-Lopez M","Bernardino G","Casu G","Prat-Gonzalez S","Vellve K","Perea RJ","Gonzalez Ballester MA","Bijnens B","Sepulveda-Martinez A","De Craene M","Crispi F","Sitges M","Butakoff C","Caralt MT","Burgos F","Pajuelo C","Blanco I"],"additional_accession":[]},"is_claimable":false,"name":"Exercise Capacity in Young Adults Born Small for Gestational Age.","description":"<h4>Importance</h4>Being born small for gestational age (SGA), approximately 10% of all births, is associated with increased risk of cardiovascular mortality in adulthood, but mechanistic pathways are unclear. Cardiac remodeling and dysfunction occur in fetuses SGA and children born SGA, but it is uncertain whether and how these changes persist into adulthood.<h4>Objective</h4>To evaluate baseline cardiac function and structure and exercise capacity in young adults born SGA.<h4>Design, setting, and participants</h4>This cohort study conducted from January 2015 to January 2018 assessed a perinatal cohort born at a tertiary university hospital in Spain between 1975 and 1995. Participants included 158 randomly selected young adults aged 20 to 40 years born SGA (birth weight below the 10th cen","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-22T09:19:34.397Z","creation":"2025-04-05T22:59:06.069Z"},"accession":"S-EPMC8576583","cross_references":{"pubmed":["34287644"],"doi":["10.1001/jamacardio.2021.2537"]}}