biostudies-literatureGardner ANIAID NIH HHSNational Institutes of HealthNIGMS NIH HHSNational Science Foundation660936https://www.ebi.ac.uk/biostudies/studies/S-EPMC8594902biostudies-literatureUnknown1CellPAINT is an interactive digital tool that allows non-expert users to create illustrations of the molecular structure of cells and viruses. We present a new release with several key enhancements, including the ability to generate custom ingredients from structure information in the Protein Data Bank, and interaction, grouping, and locking functions that streamline the creation of assemblies and illustration of large, complex scenes. An example of CellPAINT as a tool for hypothesis generation in the interpretation of cryoelectron tomograms is presented. CellPAINT is freely available at http://ccsb.scripps.edu/cellpaint.Frontiers in bioinformaticsCellPAINT: Turnkey Illustration of Molecular Cell Biology.PMC8594902R01 GM120604GM120604U54 AI150472AI150472DBI-1832184R01 GM133198R01GM133198Goodsell DSAutin LFuentes DMedina MGardner AMaritan MOlson AJGrotjahn DABarad BAfalseCellPAINT: Turnkey Illustration of Molecular Cell Biology.CellPAINT is an interactive digital tool that allows non-expert users to create illustrations of the molecular structure of cells and viruses. We present a new release with several key enhancements, including the ability to generate custom ingredients from structure information in the Protein Data Bank, and interaction, grouping, and locking functions that streamline the creation of assemblies and illustration of large, complex scenes. An example of CellPAINT as a tool for hypothesis generation in the interpretation of cryoelectron tomograms is presented. CellPAINT is freely available at http://ccsb.scripps.edu/cellpaint.2021-01-01T00:00:00Z2021 Mar2024-12-03T17:57:06.782Z2022-02-11T13:04:33.393ZS-EPMC85949023479091010.3389/fbinf.2021.660936