biostudies-literature00510Robinson RKSigne ja Ane Gyllenbergin SäätiöYrjö Jahnssonin SäätiöSigrid Juséliuksen SäätiöLastentautien TutkimussäätiöAcademy of FinlandSydäntutkimussäätiöMedical Research Council and the Wellcome TrustJuho Vainion SäätiöMedical Research CouncilFederal government of Germany, Ministry of Science and TechnologyHorizon 2020Norface: Joint Research Programme on Dynamics of InequalityWellcome TrustNovo Nordisk Fondene0259463https://www.ebi.ac.uk/biostudies/studies/S-EPMC8601551biostudies-literatureUnknown16(11)<h4>Aim</h4>Preterm birth(<37 gestational weeks) is associated with numerous adversities, however, data on positive developmental outcomes remain limited. We examined if preterm and term born(≥37 gestational weeks) adults differ in dispositional optimism/pessimism, a personality trait associated with health and wellbeing. We assessed if birth weight z-score, neurosensory impairments and parental education modified the outcome.<h4>Methods</h4>We systematically searched PubMed and Web of Science for cohort or case-control studies(born ≥ 1970) with data on gestational age and optimism/pessimism reported using the Life-Orientation-Test-Revised in adulthood(≥18 years). The three identified studies(Helsinki Study of Very Low Birth Weight Adults; Arvo Ylppö Longitudinal Study; Avon Longitudinal Study of Parents and Children) provided data for the two-step random-effects linear regression Individual-Participant-Data meta-analysis.<h4>Results</h4>Preterm and term borns did not differ on optimism(p = 0.76). Preterms scored higher on pessimism than term borns(Mean difference = 0.35, 95%Confidence Interval 0.36, 0.60, p = 0.007), although not after full adjustment. Preterm born participants, but not term born participants, with higher birth weight z-score, had higher optimism scores (0.30 raw score units per standard deviation increase, 95% CI 0.10, 0.49, p = 0.003); preterm vs term x birth weight z-score interaction p = 0.004).<h4>Conclusions</h4>Preterm and term born adults display similar optimism. In preterms, higher birth weight may foster developmental trajectories promoting more optimistic life orientations.PloS oneOptimism in adults born preterm: Systematic review and individual-participant-data meta-analysis.PMC8601551G98155081323910724363G1001357NNF18OC0034448315690; 323910, 1284859, 12848591, 1312670092731NNF19OC0057393JUG 14733280217065/Z/19/ZNNF20OC0063930MC_PC_15018MC_PC_19009Kajantie ERobinson RKAndersson SLahti-Pulkkinen MHovi PRaikkonen KHeinonen KLano AGirchenko PWolke DLemola SEriksson JG51falseOptimism in adults born preterm: Systematic review and individual-participant-data meta-analysis.<h4>Aim</h4>Preterm birth(<37 gestational weeks) is associated with numerous adversities, however, data on positive developmental outcomes remain limited. We examined if preterm and term born(≥37 gestational weeks) adults differ in dispositional optimism/pessimism, a personality trait associated with health and wellbeing. We assessed if birth weight z-score, neurosensory impairments and parental education modified the outcome.<h4>Methods</h4>We systematically searched PubMed and Web of Science for cohort or case-control studies(born ≥ 1970) with data on gestational age and optimism/pessimism reported using the Life-Orientation-Test-Revised in adulthood(≥18 years). The three identified studies(Helsinki Study of Very Low Birth Weight Adults; Arvo Ylppö Longitudinal Study; Avon Longitudinal Study of Parents and Children) provided data for the two-step random-effects linear regression Individual-Participant-Data meta-analysis.<h4>Results</h4>Preterm and term borns did not differ on optimism(p = 0.76). Preterms scored higher on pessimism than term borns(Mean difference = 0.35, 95%Confidence Interval 0.36, 0.60, p = 0.007), although not after full adjustment. Preterm born participants, but not term born participants, with higher birth weight z-score, had higher optimism scores (0.30 raw score units per standard deviation increase, 95% CI 0.10, 0.49, p = 0.003); preterm vs term x birth weight z-score interaction p = 0.004).<h4>Conclusions</h4>Preterm and term born adults display similar optimism. In preterms, higher birth weight may foster developmental trajectories promoting more optimistic life orientations.2021-01-01T00:00:00Z20212024-02-15T10:26:35.953Z2022-02-11T13:03:22.514ZS-EPMC86015513479349810.1371/journal.pone.0259463