biostudies-literatureDuque MNHLBI NIH HHS1379-1386https://www.ebi.ac.uk/biostudies/studies/S-EPMC8604382biostudies-literatureUnknown133(6)<h4>Background</h4>Total knee replacement (TKR) and total hip replacement (THR) are 2 of the most common orthopedic surgical procedures in the United States. These procedures, with fairly low mortality rates, incur significant health care costs, with almost 40% of the costs associated with post acute care. We assessed the impact of general versus neuraxial anesthesia on discharge destination and 30-day readmissions in patients who underwent total knee and hip replacement in our health system.<h4>Methods</h4>This was a retrospective cohort study of 24,684 patients undergoing total knee or hip replacement in 13 hospitals of a large health care network. Following propensity score matching, we studied the impact of type of anesthetic technique on discharge destination (primary outcome) and posAnesthesia and analgesiaImpact of Neuraxial Versus General Anesthesia on Discharge Destination in Patients Undergoing Primary Total Hip and Total Knee Replacement.PMC8604382R01 HL126711Duque MKaynar AMMonahan AMahajan AYates AJWhitehurst SSchnetz MPfalseImpact of Neuraxial Versus General Anesthesia on Discharge Destination in Patients Undergoing Primary Total Hip and Total Knee Replacement.<h4>Background</h4>Total knee replacement (TKR) and total hip replacement (THR) are 2 of the most common orthopedic surgical procedures in the United States. These procedures, with fairly low mortality rates, incur significant health care costs, with almost 40% of the costs associated with post acute care. We assessed the impact of general versus neuraxial anesthesia on discharge destination and 30-day readmissions in patients who underwent total knee and hip replacement in our health system.<h4>Methods</h4>This was a retrospective cohort study of 24,684 patients undergoing total knee or hip replacement in 13 hospitals of a large health care network. Following propensity score matching, we studied the impact of type of anesthetic technique on discharge destination (primary outcome) and pos2021-01-01T00:00:00Z2021 Dec2025-04-25T20:52:26.271Z2025-04-06T08:34:11.457ZS-EPMC86043823478432410.1213/ANE.000000000000515610.1213/ane.0000000000005156