{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liang Y"],"funding":["Fundamental Research Funds for Central Universities of the Central South University","Institut National des Sciences de l&apos;Univers, Centre National de la Recherche Scientifique","Institut National des Sciences de l'Univers, Centre National de la Recherche Scientifique"],"pagination":["122"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8607676"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["<h4>Background</h4>Codonopsis pilosula, an important medicinal plant, can accumulate certain metabolites under moderate drought stress. Endophytes are involved in the metabolite accumulations within medicinal plants. It is still unknown that the endophytes of C. pilosula are associated with the accumulations of metabolites. This study aims to investigate the promoting effect of endophytes on the accumulations of active substances in C. pilosula under drought stress.<h4>Methods</h4>High-performance liquid chromatography and high-throughput sequencing technology were performed to investigate changes in the contents of secondary metabolite and endophyte abundances of C. pilosula under drought stress, respectively. Spearman's correlation analysis was further conducted to identify the endophyti"],"journal":["Chinese medicine"],"pubmed_title":["Contents of lobetyolin, syringin, and atractylolide III in Codonopsis pilosula are related to dynamic changes of endophytes under drought stress."],"pmcid":["PMC8607676"],"funding_grant_id":["ZZ13-AQ-049","2018YFC1706302"],"pubmed_authors":["Zhang G","Liu Y","Liang Y","Dong L","Ning K","Wei G","Chen S"],"additional_accession":[]},"is_claimable":false,"name":"Contents of lobetyolin, syringin, and atractylolide III in Codonopsis pilosula are related to dynamic changes of endophytes under drought stress.","description":"<h4>Background</h4>Codonopsis pilosula, an important medicinal plant, can accumulate certain metabolites under moderate drought stress. Endophytes are involved in the metabolite accumulations within medicinal plants. It is still unknown that the endophytes of C. pilosula are associated with the accumulations of metabolites. This study aims to investigate the promoting effect of endophytes on the accumulations of active substances in C. pilosula under drought stress.<h4>Methods</h4>High-performance liquid chromatography and high-throughput sequencing technology were performed to investigate changes in the contents of secondary metabolite and endophyte abundances of C. pilosula under drought stress, respectively. Spearman's correlation analysis was further conducted to identify the endophyti","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2026-05-08T08:22:19.721Z","creation":"2022-02-11T13:11:11.71Z"},"accession":"S-EPMC8607676","cross_references":{"pubmed":["34809641"],"doi":["10.1186/s13020-021-00533-z"]}}