{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bloom MS"],"funding":["Eunice Kennedy Shriver National Institute of Child Health and Human Development","NICHD NIH HHS","National Institutes of Health","NIH HHS"],"pagination":["111820"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8616804"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["203"],"pubmed_abstract":["Perfluoroalkyl substances (PFAS) are widely distributed suspected obesogens that cross the placenta. However, few data are available to assess potential fetal effects of PFAS exposure on children's adiposity in diverse populations. To address the data gap, we estimated associations between gestational PFAS concentrations and childhood adiposity in a diverse mother-child cohort. We considered 6 PFAS in first trimester blood plasma, measured using ultra-high-performance liquid chromatography with tandem mass spectrometry, collected from non-smoking women with low-risk singleton pregnancies (n = 803). Body mass index (BMI), waist circumference (WC), fat mass, fat-free mass, and % body fat were ascertained in 4-8 year old children as measures of adiposity. We estimated associations of individu"],"journal":["Environmental research"],"pubmed_title":["Association between gestational PFAS exposure and Children's adiposity in a diverse population."],"pmcid":["PMC8616804"],"funding_grant_id":["UG3 OD023316","HHSN275200800002C","HHSN275200800013C","UG3OD023316","HHSN275200800012C","HHSN275200800028C","HHSN27500006","HHSN275201000009C","HHSN275200800014C","HHSN275200800003C","HHSN275 200800028C","HHSN275200800003I","HHSN275200800002I","UH3 OD023337"],"pubmed_authors":["Bloom MS","Pearce JL","Baumer A","Hunt KJ","Newman RB","Nageotte M","Kannan K","Grobman W","Skupski D","Neelon B","Ferguson PL","Palomares K","Commodore S","Vena JE","Tita A","Wapner R","Roberts J","Zhang C"],"additional_accession":[]},"is_claimable":false,"name":"Association between gestational PFAS exposure and Children's adiposity in a diverse population.","description":"Perfluoroalkyl substances (PFAS) are widely distributed suspected obesogens that cross the placenta. However, few data are available to assess potential fetal effects of PFAS exposure on children's adiposity in diverse populations. To address the data gap, we estimated associations between gestational PFAS concentrations and childhood adiposity in a diverse mother-child cohort. We considered 6 PFAS in first trimester blood plasma, measured using ultra-high-performance liquid chromatography with tandem mass spectrometry, collected from non-smoking women with low-risk singleton pregnancies (n = 803). Body mass index (BMI), waist circumference (WC), fat mass, fat-free mass, and % body fat were ascertained in 4-8 year old children as measures of adiposity. We estimated associations of individu","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-21T15:19:29.569Z","creation":"2025-04-21T15:19:29.569Z"},"accession":"S-EPMC8616804","cross_references":{"pubmed":["34343551"],"doi":["10.1016/j.envres.2021.111820"]}}