biostudies-literatureKim NEthe Korea Medical Device Development FundNational Research Foundation of Korea306https://www.ebi.ac.uk/biostudies/studies/S-EPMC8627606biostudies-literatureUnknown22(1)<h4>Background</h4>As lung transplantation (LTx) is becoming a standard treatment for end-stage lung disease, the use of bridging with extracorporeal membrane oxygenation (ECMO) is increasing. We examined the clinical impact of being awake during ECMO as bridging therapy in patients awaiting LTx.<h4>Methods</h4>In this single-center study, we retrospectively reviewed 241 consecutive LTx patients between October 2012 and March 2019; 64 patients received ECMO support while awaiting LTx. We divided into awake and non-awake groups and compared.<h4>Results</h4>Twenty-five patients (39.1%) were awake, and 39 (61.0%) were non-awake. The median age of awake patients was 59.0 (interquartile range, 52.5-63.0) years, and 80% of the group was men. The awake group had better post-operative outcomes thaRespiratory researchLong- and short-term clinical impact of awake extracorporeal membrane oxygenation as bridging therapy for lung transplantation.PMC8627606grant number NRF-2018R1C1B6004282project number: 202011B26Kim SYLeem AYWoo ALee SHChung KPark MSPark YKwak SHYong SHPaik HCKim HELee JGKim NEKim YSfalseLong- and short-term clinical impact of awake extracorporeal membrane oxygenation as bridging therapy for lung transplantation.<h4>Background</h4>As lung transplantation (LTx) is becoming a standard treatment for end-stage lung disease, the use of bridging with extracorporeal membrane oxygenation (ECMO) is increasing. We examined the clinical impact of being awake during ECMO as bridging therapy in patients awaiting LTx.<h4>Methods</h4>In this single-center study, we retrospectively reviewed 241 consecutive LTx patients between October 2012 and March 2019; 64 patients received ECMO support while awaiting LTx. We divided into awake and non-awake groups and compared.<h4>Results</h4>Twenty-five patients (39.1%) were awake, and 39 (61.0%) were non-awake. The median age of awake patients was 59.0 (interquartile range, 52.5-63.0) years, and 80% of the group was men. The awake group had better post-operative outcomes tha2021-01-01T00:00:00Z2021 Nov2025-04-18T14:12:02.513Z2022-02-11T13:32:03.085ZS-EPMC86276063483982110.1186/s12931-021-01905-7