{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Coceres VM"],"funding":["Conselho Nacional de Desenvolvimento Científico e Tecnológico","Agencia Nacional de Promoción Científica y Tecnológica"],"pubmed_abstract":["<i>Trichomonas vaginalis</i> and <i>Tritrichomonas foetus</i> are extracellular flagellated parasites that inhabit humans and other mammals, respectively. In addition to motility, flagella act in a variety of biological processes in different cell types, and extra-axonemal structures (EASs) have been described as fibrillar structures that provide mechanical support and act as metabolic, homeostatic, and sensory platforms in many organisms. It has been assumed that <i>T. vaginalis</i> and <i>T. foetus</i> do not have EASs. However, here, we used complementary electron microscopy techniques to reveal the ultrastructure of EASs in both parasites. Such EASs are thin filaments (3-5 nm diameter) running longitudinally along the axonemes and surrounded by the flagellar membrane, forming prominent"],"journal":["Frontiers in cellular and infection microbiology"],"pagination":["757185"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8630684"],"repository":["biostudies-literature"],"pubmed_title":["Ultrastructural and Functional Analysis of a Novel Extra-Axonemal Structure in Parasitic Trichomonads."],"pmcid":["PMC8630684"],"pubmed_authors":["Pereira-Neves A","de Miguel N","Iriarte LS","Miranda-Magalhaes A","Coceres VM","Santos de Andrade TA"],"additional_accession":[]},"is_claimable":false,"name":"Ultrastructural and Functional Analysis of a Novel Extra-Axonemal Structure in Parasitic Trichomonads.","description":"<i>Trichomonas vaginalis</i> and <i>Tritrichomonas foetus</i> are extracellular flagellated parasites that inhabit humans and other mammals, respectively. In addition to motility, flagella act in a variety of biological processes in different cell types, and extra-axonemal structures (EASs) have been described as fibrillar structures that provide mechanical support and act as metabolic, homeostatic, and sensory platforms in many organisms. It has been assumed that <i>T. vaginalis</i> and <i>T. foetus</i> do not have EASs. However, here, we used complementary electron microscopy techniques to reveal the ultrastructure of EASs in both parasites. Such EASs are thin filaments (3-5 nm diameter) running longitudinally along the axonemes and surrounded by the flagellar membrane, forming prominent","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2026-07-14T13:45:59.39Z","creation":"2025-06-01T00:05:20.197Z"},"accession":"S-EPMC8630684","cross_references":{"pubmed":["34858875"],"doi":["10.3389/fcimb.2021.757185"]}}