{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(1)"],"submitter":["Vipin A"],"funding":["National Neuroscience Institute"],"pubmed_abstract":["<h4>Background</h4>Southeast Asia represents 10% of the global population, yet little is known about regional clinical characteristics of dementia and risk factors for dementia progression. This study aims to describe the clinico-demographic profiles of dementia in Southeast Asia and investigate the association of onset-type, education, and cerebrovascular disease (CVD) on dementia progression in a real-world clinic setting.<h4>Methods</h4>In this longitudinal study, participants were consecutive series of 1606 patients with dementia from 2010 to 2019 from a tertiary memory clinic from Singapore. The frequency of dementia subtypes stratified into young-onset (YOD; <65 years age-at-onset) and late-onset dementia (LOD; ≥65 years age-at-onset) was studied. Association of onset-type (YOD or LO"],"journal":["Alzheimer's research & therapy"],"pagination":["195"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8630908"],"repository":["biostudies-literature"],"pubmed_title":["Dementia in Southeast Asia: influence of onset-type, education, and cerebrovascular disease."],"pmcid":["PMC8630908"],"pubmed_authors":["Vipin A","Satish V","Choong TM","Chiew HJ","Saffari SE","Ng ASL","Nyu MM","Koh W","Chua E","Ng KP","Kandiah N","Lim L","Silva E"],"additional_accession":[]},"is_claimable":false,"name":"Dementia in Southeast Asia: influence of onset-type, education, and cerebrovascular disease.","description":"<h4>Background</h4>Southeast Asia represents 10% of the global population, yet little is known about regional clinical characteristics of dementia and risk factors for dementia progression. This study aims to describe the clinico-demographic profiles of dementia in Southeast Asia and investigate the association of onset-type, education, and cerebrovascular disease (CVD) on dementia progression in a real-world clinic setting.<h4>Methods</h4>In this longitudinal study, participants were consecutive series of 1606 patients with dementia from 2010 to 2019 from a tertiary memory clinic from Singapore. The frequency of dementia subtypes stratified into young-onset (YOD; <65 years age-at-onset) and late-onset dementia (LOD; ≥65 years age-at-onset) was studied. Association of onset-type (YOD or LO","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-19T15:44:42.862Z","creation":"2022-02-11T13:43:57.794Z"},"accession":"S-EPMC8630908","cross_references":{"pubmed":["34847922"],"doi":["10.1186/s13195-021-00936-y"]}}