{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stockbridge MD"],"funding":["NIA NIH HHS","NIDCD NIH HHS","National Institute on Deafness and Other Communication Disorders","National Institutes of Health"],"pagination":["201-211"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8633174"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["145"],"pubmed_abstract":["Primary progressive aphasia can be distinguished into one of three variants: semantic, non-fluent/agrammatic, and logopenic. While a considerable body of work exists characterizing each variant, few prior studies have addressed the problem of optimizing behavioral assessment in a typical outpatient evaluation setting. Our aim is to examine the sensitivity and specificity of a battery of cognitive and linguistic assessments and determine optimal scores for distinguishing patients' subtype based on these instruments. This was a retrospective analysis of outpatient clinical testing of individuals with known or suspected primary progressive aphasia. Evaluations included the National Alzheimer's Coordinating Center frontotemporal lobar degeneration module and additional measures of naming, sema"],"journal":["Cortex; a journal devoted to the study of the nervous system and behavior"],"pubmed_title":["Task performance to discriminate among variants of primary progressive aphasia."],"pmcid":["PMC8633174"],"funding_grant_id":["P50 DC014664","R01 DC005375","P30 AG066507","R01 DC011317","R01 DC05375"],"pubmed_authors":["Tippett DC","Vitti E","Hillis AE","Stockbridge MD","Breining BL"],"additional_accession":[]},"is_claimable":false,"name":"Task performance to discriminate among variants of primary progressive aphasia.","description":"Primary progressive aphasia can be distinguished into one of three variants: semantic, non-fluent/agrammatic, and logopenic. While a considerable body of work exists characterizing each variant, few prior studies have addressed the problem of optimizing behavioral assessment in a typical outpatient evaluation setting. Our aim is to examine the sensitivity and specificity of a battery of cognitive and linguistic assessments and determine optimal scores for distinguishing patients' subtype based on these instruments. This was a retrospective analysis of outpatient clinical testing of individuals with known or suspected primary progressive aphasia. Evaluations included the National Alzheimer's Coordinating Center frontotemporal lobar degeneration module and additional measures of naming, sema","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-05T09:43:20.255Z","creation":"2025-04-05T09:43:20.255Z"},"accession":"S-EPMC8633174","cross_references":{"pubmed":["34742101"],"doi":["10.1016/j.cortex.2021.09.015"]}}