biostudies-literatureUnknown45Gerardin P<h4>Objectives</h4>The purpose of this cohort study was to develop two scores able to differentiate coronavirus 2019 (COVID-19) from dengue and other febrile illnesses (OFIs).<h4>Methods</h4>All subjects suspected of COVID-19 who attended the SARS-CoV-2 testing center of Saint-Pierre hospital, Reunion, between March 23 and May 10, 2020, were assessed for identifying predictors of both infectious diseases from a multinomial logistic regression model. Two scores were developed after weighting the odd ratios then validated by bootstrapping.<h4>Results</h4>Over 49 days, 80 COVID-19, 60 non-severe dengue and 872 OFIs were diagnosed. The translation of the best fit model yielded two scores composed of 11 criteria: contact with a COVID-19 positive case (+3 points for COVID-19; 0 point for dengue)Travel medicine and infectious disease102232https://www.ebi.ac.uk/biostudies/studies/S-EPMC8656151biostudies-literatureDifferentiating COVID-19 and dengue from other febrile illnesses in co-epidemics: Development and internal validation of COVIDENGUE scores.PMC8656151Accot FMaillard OAndry FLegrand FLevin CBruneau LBertolotti AManaquin RPoubeau PGerardin PfalseDifferentiating COVID-19 and dengue from other febrile illnesses in co-epidemics: Development and internal validation of COVIDENGUE scores.<h4>Objectives</h4>The purpose of this cohort study was to develop two scores able to differentiate coronavirus 2019 (COVID-19) from dengue and other febrile illnesses (OFIs).<h4>Methods</h4>All subjects suspected of COVID-19 who attended the SARS-CoV-2 testing center of Saint-Pierre hospital, Reunion, between March 23 and May 10, 2020, were assessed for identifying predictors of both infectious diseases from a multinomial logistic regression model. Two scores were developed after weighting the odd ratios then validated by bootstrapping.<h4>Results</h4>Over 49 days, 80 COVID-19, 60 non-severe dengue and 872 OFIs were diagnosed. The translation of the best fit model yielded two scores composed of 11 criteria: contact with a COVID-19 positive case (+3 points for COVID-19; 0 point for dengue)2022-01-01T00:00:00Z2022 Jan-Feb2025-05-29T21:12:18.927Z2025-05-29T21:12:18.927ZS-EPMC86561513489664910.1016/j.tmaid.2021.102232