biostudies-literatureMartin KDNational Institute of Neurological Disorders and StrokeNIA NIH HHSU.S. Department of Health and Human ServicesNINDS NIH HHSNational Institutes of HealthNational Institute on Aging106848https://www.ebi.ac.uk/biostudies/studies/S-EPMC8658048biostudies-literatureUnknown153Low socioeconomic position (SEP) across the lifecourse is associated with Type 2 diabetes (T2DM). We examined whether these economic disparities differ by race and sex. We included 5448 African American (AA) and white participants aged ≥45 years from the national (United States) REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort without T2DM at baseline (2003-07). Incident T2DM was defined by fasting glucose ≥126 mg/dL, random glucose ≥200 mg/dL, or using T2DM medications at follow-up (2013-16). Derived SEP scores in childhood (CSEP) and adulthood (ASEP) were used to calculate a cumulative (CumSEP) score. Social mobility was defined as change in SEP. We fitted race-stratified logistic regression models to estimate the association between each lifecourse SEP indicator Preventive medicineLifecourse socioeconomic position and diabetes incidence in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, 2003 to 2016.PMC8658048U01 NS041588R01 AG039588Bennett AHoward VJBullard KMImperatore GMartin KDMcClure LAWu CUnverzagt FCunningham SBeckles GLCarson APGlymour MMfalseLifecourse socioeconomic position and diabetes incidence in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, 2003 to 2016.Low socioeconomic position (SEP) across the lifecourse is associated with Type 2 diabetes (T2DM). We examined whether these economic disparities differ by race and sex. We included 5448 African American (AA) and white participants aged ≥45 years from the national (United States) REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort without T2DM at baseline (2003-07). Incident T2DM was defined by fasting glucose ≥126 mg/dL, random glucose ≥200 mg/dL, or using T2DM medications at follow-up (2013-16). Derived SEP scores in childhood (CSEP) and adulthood (ASEP) were used to calculate a cumulative (CumSEP) score. Social mobility was defined as change in SEP. We fitted race-stratified logistic regression models to estimate the association between each lifecourse SEP indicator 2021-01-01T00:00:00Z2021 Dec2025-04-25T20:53:14.032Z2025-04-06T08:34:22.975ZS-EPMC86580483467308010.1016/j.ypmed.2021.106848