{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rangan GK"],"funding":["National Health and Medical Research Council","PKD Australia"],"pagination":["e046539"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8663108"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(12)"],"pubmed_abstract":["<h4>Introduction</h4>Excessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical characteristics and outcomes of hyponatraemia associated with excess water intake.<h4>Methods</h4>This review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All studies (case reports, observational or interventional studies) reporting excess water intake and hyponatraemia in adults (1946-2019) were included.<h4>Results</h4>A total of 2970 articles were identified and 177 were included (88.7% case reports), consisting of 590 patients. The mean age was 46±16 years (95% CI 44 to 48 years), 47% female, 52% had a chronic psychiatric disorder and 31% had no underlying condition. The m"],"journal":["BMJ open"],"pubmed_title":["Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review."],"pmcid":["PMC8663108"],"funding_grant_id":["N/A","1138533","1164128"],"pubmed_authors":["Chandra AN","Zhang MM","Dorani N","Munt A","Abu-Zarour L","Lau HC","Wong AT","Rangan GK","Howell M","Zhang JQJ","Rangan A","Saravanabavan S"],"additional_accession":[]},"is_claimable":false,"name":"Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review.","description":"<h4>Introduction</h4>Excessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical characteristics and outcomes of hyponatraemia associated with excess water intake.<h4>Methods</h4>This review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All studies (case reports, observational or interventional studies) reporting excess water intake and hyponatraemia in adults (1946-2019) were included.<h4>Results</h4>A total of 2970 articles were identified and 177 were included (88.7% case reports), consisting of 590 patients. The mean age was 46±16 years (95% CI 44 to 48 years), 47% female, 52% had a chronic psychiatric disorder and 31% had no underlying condition. The m","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-19T16:20:38.28Z","creation":"2024-12-03T16:40:31.19Z"},"accession":"S-EPMC8663108","cross_references":{"pubmed":["34887267"],"doi":["10.1136/bmjopen-2020-046539"]}}