{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["97(20)"],"submitter":["Besse-Pinot E"],"pubmed_abstract":["<h4>Background and objectives</h4>To determine whether patients with Parkinson disease (PD) eligible for subthalamic nucleus deep brain stimulation (STN-DBS) with probable REM sleep behavior disorder (RBD) preoperatively could be more at risk of poorer motor, nonmotor, and quality of life outcomes 12 months after surgery compared to those without RBD.<h4>Methods</h4>We analyzed the preoperative clinical profile of 448 patients with PD from a French multicentric prospective study (PREDISTIM) according to the presence or absence of probable RBD based on the RBD Single Question and RBD Screening Questionnaire. Among the 215 patients with PD with 12 months of follow-up after STN-DBS, we compared motor, cognitive, psycho-behavioral profile, and quality of life outcomes in patients with (pre-opR"],"journal":["Neurology"],"pagination":["e1994-e2006"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8672430"],"repository":["biostudies-literature"],"pubmed_title":["Preoperative REM Sleep Behavior Disorder and Subthalamic Nucleus Deep Brain Stimulation Outcome in Parkinson Disease 1 Year After Surgery."],"pmcid":["PMC8672430"],"pubmed_authors":["Polo DG","Fetter DD","Viard DR","Olivier PR","Regis PJ","Witjas DT","Benatru I","Delmaire DC","Houvenaghel JF","Ferrier V","Durif F","Krim DE","Bioux S","Harroch E","Lehericy S","Roze E","Blanchard J","Colnat PS","Belamri L","Moreau DC","Debilly DB","Corvol JC","Remy PG","Derrey PS","Besse-Pinot E","Grimaldi DS","Bourdain DF","Njosse YT","Bannier DS","Djemmane L","Girodana DC","Devos D","Debilly B","Vernon ML","Derkinderen PP","Faustini A","Girard PN","Voirin DJ","Rouaud DT","Rieu I","Ollivier DM","Mangin JF","Meneret A","Huiban C","Lopez D","Bonnet M","Tir DM","Potey C","Pereira B","Lagha-Boukbiza O","Benchetrit E","Karsenti DP","Carron DR","Philippe DC","Bonnet DA","Philippe DP","Philippe DR","Lacoste DM","Engelhardt DJ","Molinier-Blossier DS","Giordana C","Gebus DO","Spatola DG","Vrillac J","Giordana DB","Brefel Courbon DC","Drapier S","Ouk T","Chupin M","Laugeais MV","Jean Luc PH","Vincent DR","Derost P","Czernecki V","Mariani LL","Seling A","Severine LD","Moreau C","Duhamel A","Aix S","Ory Magne DF","Meyer M","Chaussemy DD","Laurencin DC","Jarraya PB","CalvierAuffray DE","Manssouri A","D'Hardemare DV","Derost DP","Simon DE","Ameli DR","Cornu P","Magnaudet C","Maltete D","Reyns PN","Delorme C","Bozon F","Huet C","Graveleau DP","Leclerc P","Tison PF","Anne F","Gers E","Karachi C","Hubsch C","Marques A","Afanassiev DV","Defebvre PL","LaghaBoukbiza DO","Pineau F","Lemaire PJJ","Rocher L","Baille DG","Leplus DA","Phillips C","Klinger H","Fievet F","Lefaucheur DR","Hartmann A","Navarro S","Rolland AS","Deruet AL","Eusebio PA","Eusebio A","Delval PA","Simonetta Moreau DM","Caire PF","Fantini ML","Guehl D","Jean-Christophe Ferre D","Rouaud T","Chassain C","Ory S","Fluchere DF","Lefort C","Haegelen PC","Fruit C","Schuler B","Berthezene PY","Ziegler DM","Kestens F","Facon L","Delliaux MM","Lebouteux DM","Sarrail M","Jean-Pierre Pruvo P","El Mountassir F","Durif PF","Decrocq DC","Dujardin PK","Vidal T","Savatowky DJ","Branchard O","Brion MM","Guehl PD","Worbe Y","GuimeraesCosta R","Jarraya B","Beal DC","Dupuy V E","Ziegler DF","Santraine MV","Fischer C","Cointepas Y","Kreisler D","Gay D","Cuny PE","Delfini M","Solene DA","Kremer DS","Leh DF","Nunes A","Auzou N","Blin S","Derenaucourt V","Hainque E","Bailet B","Metereau E","Leclercq C","Anne-Gaelle Corbille D","Welter ML","CormierDequaire F","Anheim PM","Gardel DB","Carriere DN","Touzet DG","Dillier C","Meissner PW","Ihle J","Chaynes PP","Fontaine DD","Isabelle DB","Rascol O","Nakache C","Jean-Marc Constans P","Sophie B","Marie des Neiges Santin D","Bonice R","DamonPerriere DN","Mantisi L","Chatelain A","Loubeyre M","You H","Tranchant PC","Olivier DC","Grolez DG","Lacomblez L","Hopes L","Philippe Brandel DJ","Damier PP","Marse DC","Gele P","Thobois S","Mengin DA","Deplanque D","Sylvie DR","Hopes Dr DL","Longato N","Albert Lotterie DJ","Krystkowiak PP","Mondot DL","Emilie R","Lefranc DM","Accart B","Magne DN","Arbus PC","Mertens DP","Hubsch DC","Tir M","Maltete PD","Lopes DR","Duflot F","Jarry N","Kuchcinski DG","Thobois PS","Corvol Marie-Vidailhet JC","Verin PM","Predistim Study Group","Dumont MJ","Joly H","Burbaud PP","Boulin DA","Pouliquen D","Grabli D","Bonneville PF","Marques DA","Danaila DT","Kardous DR","Durand E","Pleuvret MM","Dautrevaux MN","Bliaux E","Sophie DD","Chabel M","Delaby L","Benoit PB","Annie G","Jean-Philippe Azulay P","Schmitt E","Montaut DS","Wannepain S","Welaratne A"],"additional_accession":[]},"is_claimable":false,"name":"Preoperative REM Sleep Behavior Disorder and Subthalamic Nucleus Deep Brain Stimulation Outcome in Parkinson Disease 1 Year After Surgery.","description":"<h4>Background and objectives</h4>To determine whether patients with Parkinson disease (PD) eligible for subthalamic nucleus deep brain stimulation (STN-DBS) with probable REM sleep behavior disorder (RBD) preoperatively could be more at risk of poorer motor, nonmotor, and quality of life outcomes 12 months after surgery compared to those without RBD.<h4>Methods</h4>We analyzed the preoperative clinical profile of 448 patients with PD from a French multicentric prospective study (PREDISTIM) according to the presence or absence of probable RBD based on the RBD Single Question and RBD Screening Questionnaire. Among the 215 patients with PD with 12 months of follow-up after STN-DBS, we compared motor, cognitive, psycho-behavioral profile, and quality of life outcomes in patients with (pre-opR","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-05-29T16:11:44.453Z","creation":"2025-04-04T09:32:09.077Z"},"accession":"S-EPMC8672430","cross_references":{"pubmed":["34667082"],"doi":["10.1212/wnl.0000000000012862","10.1212/WNL.0000000000012862"]}}