{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sandoval-Insausti H"],"funding":["NIEHS NIH HHS","NHLBI NIH HHS","NCI NIH HHS","National Institutes of Health"],"pagination":["106744"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8679006"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["156"],"pubmed_abstract":["<h4>Background</h4>Conventionally grown fruits and vegetables (FVs) are the main source of general population exposure to pesticide residues.<h4>Objective</h4>To evaluate the relation of intake of high- and low-pesticide-residue FVs with cancer risk.<h4>Methods</h4>We followed 150,830 women (Nurses' Health Study, 1998-2016, and Nurses' Health Study II, 1999-2017) and 29,486 men (Health Professionals Follow-up Study, 1998-2016) without a history of cancer. We ascertained FV intake via validated food frequency questionnaires and categorized FVs as having high or low pesticide residue levels based on USDA surveillance data. We used Cox proportional hazards models to estimate hazard ratios (HR) and 95% confidence intervals (CI) of total and site-specific cancer related to quintiles of high- an"],"journal":["Environment international"],"pubmed_title":["Intake of fruits and vegetables by pesticide residue status in relation to cancer risk."],"pmcid":["PMC8679006"],"funding_grant_id":["R01 HL034594","P30 ES000002","U01 CA167552","U01 HL145386","P01 CA087969","T32 CA009001","U01 CA176726","R24 ES028521","R01 HL088521","UM1 CA186107"],"pubmed_authors":["Birmann B","Willett WC","Hart JE","Minguez-Alarcon L","Chavarro JE","Lee DH","Sandoval-Insausti H","Wang S","Chiu YH","Heather Eliassen A","Ardisson Korat AV","Laden F"],"additional_accession":[]},"is_claimable":false,"name":"Intake of fruits and vegetables by pesticide residue status in relation to cancer risk.","description":"<h4>Background</h4>Conventionally grown fruits and vegetables (FVs) are the main source of general population exposure to pesticide residues.<h4>Objective</h4>To evaluate the relation of intake of high- and low-pesticide-residue FVs with cancer risk.<h4>Methods</h4>We followed 150,830 women (Nurses' Health Study, 1998-2016, and Nurses' Health Study II, 1999-2017) and 29,486 men (Health Professionals Follow-up Study, 1998-2016) without a history of cancer. We ascertained FV intake via validated food frequency questionnaires and categorized FVs as having high or low pesticide residue levels based on USDA surveillance data. We used Cox proportional hazards models to estimate hazard ratios (HR) and 95% confidence intervals (CI) of total and site-specific cancer related to quintiles of high- an","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-05T11:27:39.609Z","creation":"2025-04-05T11:27:39.609Z"},"accession":"S-EPMC8679006","cross_references":{"pubmed":["34256297"],"doi":["10.1016/j.envint.2021.106744"]}}