{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Lim ZW"],"pubmed_abstract":["<h4>Introduction</h4>An important clinical feature of metabolic syndrome is abdominal obesity. Microalbuminuria is important in predicting the risk of cardiovascular and renal complications in abdominal obesity patients. However, the association between microalbuminuria polymorphism and abdominal obesity has not been conducted. The objective of this study is to analyze the genetic polymorphism of microalbuminuria in participants with metabolically unhealthy obesity (MUO).<h4>Methods</h4>Among 1325 MUO participants, we identified genomic loci underlying those with microalbuminuria, compared to those without microalbuminuria. Single nucleotide polymorphisms (SNPs) were selected with P < 1 × 10<sup>-5</sup> from the Manhattan plot. Multivariable linear regression and analysis of variance were"],"journal":["Journal of inflammation research"],"pagination":["6833-6844"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8684407"],"repository":["biostudies-literature"],"pubmed_title":["Polymorphism rs10105606 of <i>LPL</i> as a Novel Risk Factor for Microalbuminuria."],"pmcid":["PMC8684407"],"pubmed_authors":["Lim ZW","Chen WL"],"additional_accession":[]},"is_claimable":false,"name":"Polymorphism rs10105606 of <i>LPL</i> as a Novel Risk Factor for Microalbuminuria.","description":"<h4>Introduction</h4>An important clinical feature of metabolic syndrome is abdominal obesity. Microalbuminuria is important in predicting the risk of cardiovascular and renal complications in abdominal obesity patients. However, the association between microalbuminuria polymorphism and abdominal obesity has not been conducted. The objective of this study is to analyze the genetic polymorphism of microalbuminuria in participants with metabolically unhealthy obesity (MUO).<h4>Methods</h4>Among 1325 MUO participants, we identified genomic loci underlying those with microalbuminuria, compared to those without microalbuminuria. Single nucleotide polymorphisms (SNPs) were selected with P < 1 × 10<sup>-5</sup> from the Manhattan plot. Multivariable linear regression and analysis of variance were","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-06-01T01:59:12.507Z","creation":"2025-06-01T01:59:12.507Z"},"accession":"S-EPMC8684407","cross_references":{"pubmed":["34934334"],"doi":["10.2147/JIR.S338010"]}}