{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["33(2)"],"submitter":["Ono M"],"pubmed_abstract":["<h4>Objectives</h4>With improvements in early survival after the stage I palliation (S1P) Norwood procedure for hypoplastic left heart syndrome (HLHS) and its variants, inter-stage death accounts for an increasing proportion of mortality. Our aim was to identify the risk factors for inter-stage mortality.<h4>Methods</h4>The records of 322 neonates with HLHS or a variant who underwent the Norwood procedure at our centre between 2001 and 2019 were retrospectively analysed.<h4>Results</h4>The diagnoses included 271 neonates with HLHS (84%) and 51 with variants (16%). Aortic atresia was observed in 138 (43%) patients, mitral atresia in 91 (28%), extracardiac anomalies in 42 (13%) and genetic disorder in 14 (4%). The median age and weight of the patients at the S1P Norwood procedure were 9 (int"],"journal":["Interactive cardiovascular and thoracic surgery"],"pagination":["218-226"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8691571"],"repository":["biostudies-literature"],"pubmed_title":["Preoperative risk factors influencing inter-stage mortality after the Norwood procedure."],"pmcid":["PMC8691571"],"pubmed_authors":["Ono M","Horer J","Wallner M","Ewert P","Cleuziou J","Burri M","Hager A","Lemmer J","Strbad M","Kido T"],"additional_accession":[]},"is_claimable":false,"name":"Preoperative risk factors influencing inter-stage mortality after the Norwood procedure.","description":"<h4>Objectives</h4>With improvements in early survival after the stage I palliation (S1P) Norwood procedure for hypoplastic left heart syndrome (HLHS) and its variants, inter-stage death accounts for an increasing proportion of mortality. Our aim was to identify the risk factors for inter-stage mortality.<h4>Methods</h4>The records of 322 neonates with HLHS or a variant who underwent the Norwood procedure at our centre between 2001 and 2019 were retrospectively analysed.<h4>Results</h4>The diagnoses included 271 neonates with HLHS (84%) and 51 with variants (16%). Aortic atresia was observed in 138 (43%) patients, mitral atresia in 91 (28%), extracardiac anomalies in 42 (13%) and genetic disorder in 14 (4%). The median age and weight of the patients at the S1P Norwood procedure were 9 (int","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jul","modification":"2026-07-09T12:06:07.886Z","creation":"2025-04-05T14:43:19.781Z"},"accession":"S-EPMC8691571","cross_references":{"pubmed":["33948647"],"doi":["10.1093/icvts/ivab073"]}}