{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(8)"],"submitter":["Xing WL"],"pubmed_abstract":["A transition-metal-free decarboxylative thiolation protocol is reported in which primary, secondary, tertiary (hetero)aryl acetates and α-CN substituted acetates undergo the decarboxylative thiolation smoothly, to deliver a variety of functionalized aryl alkyl sulfides in moderate to excellent yields. Aryl diselenides are also amenable substrates for construction of C-Se bonds under the simple and mild reaction conditions. Moreover, the protocol is successfully applied to the late-stage modification of pharmaceutical carboxylates with satisfactory chemoselectivity and functional-group compatibility."],"journal":["RSC advances"],"pagination":["4593-4597"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8694499"],"repository":["biostudies-literature"],"pubmed_title":["Transition-metal-free decarboxylative thiolation of stable aliphatic carboxylates."],"pmcid":["PMC8694499"],"pubmed_authors":["Xing WL","Liu DG","Fu MC"],"additional_accession":[]},"is_claimable":false,"name":"Transition-metal-free decarboxylative thiolation of stable aliphatic carboxylates.","description":"A transition-metal-free decarboxylative thiolation protocol is reported in which primary, secondary, tertiary (hetero)aryl acetates and α-CN substituted acetates undergo the decarboxylative thiolation smoothly, to deliver a variety of functionalized aryl alkyl sulfides in moderate to excellent yields. Aryl diselenides are also amenable substrates for construction of C-Se bonds under the simple and mild reaction conditions. Moreover, the protocol is successfully applied to the late-stage modification of pharmaceutical carboxylates with satisfactory chemoselectivity and functional-group compatibility.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jan","modification":"2025-04-22T22:04:12.083Z","creation":"2025-04-06T03:55:18.376Z"},"accession":"S-EPMC8694499","cross_references":{"pubmed":["35424417"],"doi":["10.1039/d1ra00063b"]}}