{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(11)"],"submitter":["Horst FH"],"funding":["Universidade de Brasília","Fundação de Apoio à Pesquisa do Distrito Federal","Conselho Nacional de Desenvolvimento Científico e Tecnológico","Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","Laboratório Nacional de Luz Síncrotron"],"pubmed_abstract":["Bioactive carbon dots (C-dots) with <i>ca.</i> 4 nm were successfully produced with singular photophysical properties, low-toxicity and interesting immunological response. The optical properties of the C-dots were investigated and the \"light-up\" behaviour enabled them to be explored in glucose detection and bioimaging experiments (mitochondrial selective probe). C-dots were not selective to the tumour region and several fluorescent spots were visualized spread on animal bodies. The histology investigations showed that cancer-bearing mice treated with C-dots presented a large number of regions with necrosis and inflammatory infiltrates, which were not identified for cancer-bearing mice without the treatment. These results suggested that C-dots have the potential to be explored as an immune "],"journal":["RSC advances"],"pagination":["6346-6352"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8694864"],"repository":["biostudies-literature"],"pubmed_title":["From cow manure to bioactive carbon dots: a light-up probe for bioimaging investigations, glucose detection and potential immunotherapy agent for melanoma skin cancer."],"pmcid":["PMC8694864"],"pubmed_authors":["Rodrigues CVDS","Carvalho PHPR","Correa JR","Leite AM","Garcia MP","Alotaibi S","Chaves SB","Neto BAD","Henini M","Rodrigues MO","Horst FH","Azevedo RB"],"additional_accession":[]},"is_claimable":false,"name":"From cow manure to bioactive carbon dots: a light-up probe for bioimaging investigations, glucose detection and potential immunotherapy agent for melanoma skin cancer.","description":"Bioactive carbon dots (C-dots) with <i>ca.</i> 4 nm were successfully produced with singular photophysical properties, low-toxicity and interesting immunological response. The optical properties of the C-dots were investigated and the \"light-up\" behaviour enabled them to be explored in glucose detection and bioimaging experiments (mitochondrial selective probe). C-dots were not selective to the tumour region and several fluorescent spots were visualized spread on animal bodies. The histology investigations showed that cancer-bearing mice treated with C-dots presented a large number of regions with necrosis and inflammatory infiltrates, which were not identified for cancer-bearing mice without the treatment. These results suggested that C-dots have the potential to be explored as an immune ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Feb","modification":"2025-04-25T23:01:06.172Z","creation":"2025-04-06T09:13:36.105Z"},"accession":"S-EPMC8694864","cross_references":{"pubmed":["35423156"],"doi":["10.1039/d0ra10859f"]}}