biostudies-literatureWu WNational Natural Science Foundation of China14710-14716https://www.ebi.ac.uk/biostudies/studies/S-EPMC8697811biostudies-literatureUnknown11(24)An effective process for synthesis of alkyl polyglycosides (APG) was developed using SO₃H-functionalized ionic liquids (SFILs) as catalysts. Four SFILs, [PSmim][HSO₄], [PSmim][<i>p</i>TSA], [PSPy][HSO₄] and [PSPy][<i>p</i>TSA], were designed and synthesized for APG synthesis. The results indicated that [PSmim][HSO₄] shows the best catalytic performance among these four SFILs, which has a great agreement with the order of their acidities. When the [PSmim][HSO₄] was used as catalyst, the reaction time could be decreased from 24 h to 8 h, and molar ration of <i>n</i>-octanol to glucose could be decreased from 5 : 1 to 3 : 1 under the optimization reaction conditions. In addition, the [PSmim][HSO₄] could be easily regenerated anRSC advancesSynthesis of alkyl polyglycosides using SO₃H-functionalized ionic liquids as catalysts.PMC8697811214360102207832351574215Yu MWang BHai BGao HWu WNie YfalseSynthesis of alkyl polyglycosides using SO₃H-functionalized ionic liquids as catalysts.An effective process for synthesis of alkyl polyglycosides (APG) was developed using SO₃H-functionalized ionic liquids (SFILs) as catalysts. Four SFILs, [PSmim][HSO₄], [PSmim][<i>p</i>TSA], [PSPy][HSO₄] and [PSPy][<i>p</i>TSA], were designed and synthesized for APG synthesis. The results indicated that [PSmim][HSO₄] shows the best catalytic performance among these four SFILs, which has a great agreement with the order of their acidities. When the [PSmim][HSO₄] was used as catalyst, the reaction time could be decreased from 24 h to 8 h, and molar ration of <i>n</i>-octanol to glucose could be decreased from 5 : 1 to 3 : 1 under the optimization reaction conditions. In addition, the [PSmim][HSO₄] could be easily regenerated an2021-01-01T00:00:00Z2021 Apr2025-04-25T22:31:16.57Z2025-04-06T09:04:51.228ZS-EPMC86978113542399510.1039/d1ra00337b