{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Akhavan M"],"funding":["National Institute for Medical Research Development","Mazandaran University of Medical Sciences"],"pagination":["14755-14768"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8698206"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(24)"],"pubmed_abstract":["An efficient, green, one-pot, and three-component protocol has been reported for the stereoselective synthesis of a new class of spiro thiazolidines. A series of spiro-heterocycle derivatives were produced stereoselectively in high yields by the reaction of 5-arylidene thiazolidine-2,4-diones, isatin, and secondary amino acids in the presence of MnCoCuFe<sub>2</sub>O<sub>4</sub>@l-proline (MCCFe<sub>2</sub>O<sub>4</sub>@l-proline) magnetic nanorods as a novel nanocatalyst. The synthesized catalyst was fully characterized for thermal stability, magnetic properties, and other physicochemical properties <i>via</i> numerous techniques. It was applied as an efficient and reusable catalyst for the synthesis of <i>endo</i>-isomers of spirocyclic pyrrolidine/pyrrolizidine/pyrrolothiazolidine deriv"],"journal":["RSC advances"],"pubmed_title":["Stereoselective synthesis of spirocyclic pyrrolidines/pyrrolizidines/pyrrolothiazolidines using l-proline functionalized manganese ferrite nanorods as a novel heterogeneous catalyst."],"pmcid":["PMC8698206"],"funding_grant_id":["971338"],"pubmed_authors":["Akhavan M","Bekhradnia A"],"additional_accession":[]},"is_claimable":false,"name":"Stereoselective synthesis of spirocyclic pyrrolidines/pyrrolizidines/pyrrolothiazolidines using l-proline functionalized manganese ferrite nanorods as a novel heterogeneous catalyst.","description":"An efficient, green, one-pot, and three-component protocol has been reported for the stereoselective synthesis of a new class of spiro thiazolidines. A series of spiro-heterocycle derivatives were produced stereoselectively in high yields by the reaction of 5-arylidene thiazolidine-2,4-diones, isatin, and secondary amino acids in the presence of MnCoCuFe<sub>2</sub>O<sub>4</sub>@l-proline (MCCFe<sub>2</sub>O<sub>4</sub>@l-proline) magnetic nanorods as a novel nanocatalyst. The synthesized catalyst was fully characterized for thermal stability, magnetic properties, and other physicochemical properties <i>via</i> numerous techniques. It was applied as an efficient and reusable catalyst for the synthesis of <i>endo</i>-isomers of spirocyclic pyrrolidine/pyrrolizidine/pyrrolothiazolidine deriv","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2025-04-04T19:58:02.38Z","creation":"2025-04-04T19:58:02.38Z"},"accession":"S-EPMC8698206","cross_references":{"pubmed":["35423973"],"doi":["10.1039/d1ra00841b"]}}