{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhou JJ"],"funding":["Laboratory for Lingnan Modern Agriculture","Wuhan Applied Foundational Frontier Project","China Agriculture Research System of MOF and MARA","The National Key Research and Development Program"],"pagination":["1311"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8698383"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(12)"],"pubmed_abstract":["Intermuscular bones (IBs) are small spicule-like bones located in the myosepta of basal teleosts, which negatively affect the edibleness and economic value of fish. Blunt snout bream (<i>Megalobrama amblycephala</i>, with epineural and epipleural IBs) and tilapia (<i>Oreochromis niloticus</i>, without epineural and epipleural IBs) are two major aquaculture species and ideal models for studying the formation mechanisms of fish IBs. Here, we compared myosepta development between <i>M. amblycephala</i> and <i>O. niloticus</i>, based on histological analysis, transcriptome profiling, and expression analysis of bone-related genes. The histological results showed that dye condensation began to appear in the myosepta 20 days post hatching (dph) in <i>M. amblycephala</i>, and IBs could be clearly "],"journal":["Biology"],"pubmed_title":["Comparison of Myosepta Development and Transcriptome Profiling between Blunt Snout Bream with and Tilapia without Intermuscular Bones."],"pmcid":["PMC8698383"],"funding_grant_id":["2020020601012253","2018YFD0900102","CARS-46-08","NZ2021011"],"pubmed_authors":["Zhou JJ","Chang YJ","Wang XD","Gao ZX","Liao Q","Chen YL","Shi RH"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of Myosepta Development and Transcriptome Profiling between Blunt Snout Bream with and Tilapia without Intermuscular Bones.","description":"Intermuscular bones (IBs) are small spicule-like bones located in the myosepta of basal teleosts, which negatively affect the edibleness and economic value of fish. Blunt snout bream (<i>Megalobrama amblycephala</i>, with epineural and epipleural IBs) and tilapia (<i>Oreochromis niloticus</i>, without epineural and epipleural IBs) are two major aquaculture species and ideal models for studying the formation mechanisms of fish IBs. Here, we compared myosepta development between <i>M. amblycephala</i> and <i>O. niloticus</i>, based on histological analysis, transcriptome profiling, and expression analysis of bone-related genes. The histological results showed that dye condensation began to appear in the myosepta 20 days post hatching (dph) in <i>M. amblycephala</i>, and IBs could be clearly ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2026-04-08T07:06:44.479Z","creation":"2022-02-11T14:36:52.825Z"},"accession":"S-EPMC8698383","cross_references":{"pubmed":["34943226"],"doi":["10.3390/biology10121311"]}}