{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["102(4)"],"submitter":["Wang H"],"pubmed_abstract":["One SARS-CoV-2-positive sample demonstrated impaired detection of the N1 target by RT-PCR using US CDC primer/probe sets. A 3 nucleotide deletion was discovered that overlaps the forward primer binding site. This finding underscores the importance of continued SARS-CoV-2 mutation surveillance and assessment of the impact on diagnostic test performance."],"journal":["Diagnostic microbiology and infectious disease"],"pagination":["115631"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8715644"],"repository":["biostudies-literature"],"pubmed_title":["A deletion in the N gene of SARS-CoV-2 may reduce test sensitivity for detection of SARS-CoV-2."],"pmcid":["PMC8715644"],"pubmed_authors":["Lucyshyn JM","Magrini V","Jean S","Leber AL","Wang H","Wilson RK","Wilson SA","McGrath S"],"additional_accession":[]},"is_claimable":false,"name":"A deletion in the N gene of SARS-CoV-2 may reduce test sensitivity for detection of SARS-CoV-2.","description":"One SARS-CoV-2-positive sample demonstrated impaired detection of the N1 target by RT-PCR using US CDC primer/probe sets. A 3 nucleotide deletion was discovered that overlaps the forward primer binding site. This finding underscores the importance of continued SARS-CoV-2 mutation surveillance and assessment of the impact on diagnostic test performance.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2025-04-26T19:49:17.239Z","creation":"2022-02-11T16:17:53.624Z"},"accession":"S-EPMC8715644","cross_references":{"pubmed":["35045382"],"doi":["10.1016/j.diagmicrobio.2021.115631"]}}