{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huang C"],"funding":["Taishan Scholar Program","National Natural Science Foundation of China","the Academic Promotion Program and Innovation Project of Shandong First Medical University"],"pagination":["18-30"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8725936"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(1)"],"pubmed_abstract":["Corneal neovascularization is a serious corneal pathological change caused by various factors. The drug delivery system is of great significance for the effective treatment of corneal neovascularization. Herein, we developed and characterized a monolith/hydrogel composite as the triamcinolone acetonide (TA) carrier for curing corneal neovascularization. The composite was prepared by photo-initiated free radical polymerization of multi-methacrylate substituted dodecamine organic molecular cage and post-modified by the sequential photo-initiated free radical polymerization of acrylated gelatin. The globular morphology and structural property of as-prepared composites were evaluated by scanning electron microscopy, Fourier-transform infrared spectroscopy and solid-state cross polarization mag"],"journal":["Drug delivery"],"pubmed_title":["Monolith/Hydrogel composites as triamcinolone acetonide carriers for curing corneal neovascularization in mice by inhibiting the fibrinolytic system."],"pmcid":["PMC8725936"],"funding_grant_id":["81870639","82070923","201812150","2019RC009","20150215"],"pubmed_authors":["Chao W","Huang C","Qi X","Chen H","Wang H","Gao H"],"additional_accession":[]},"is_claimable":false,"name":"Monolith/Hydrogel composites as triamcinolone acetonide carriers for curing corneal neovascularization in mice by inhibiting the fibrinolytic system.","description":"Corneal neovascularization is a serious corneal pathological change caused by various factors. The drug delivery system is of great significance for the effective treatment of corneal neovascularization. Herein, we developed and characterized a monolith/hydrogel composite as the triamcinolone acetonide (TA) carrier for curing corneal neovascularization. The composite was prepared by photo-initiated free radical polymerization of multi-methacrylate substituted dodecamine organic molecular cage and post-modified by the sequential photo-initiated free radical polymerization of acrylated gelatin. The globular morphology and structural property of as-prepared composites were evaluated by scanning electron microscopy, Fourier-transform infrared spectroscopy and solid-state cross polarization mag","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2026-06-02T16:14:51.606Z","creation":"2022-02-11T14:33:56.434Z"},"accession":"S-EPMC8725936","cross_references":{"pubmed":["34962228"],"doi":["10.1080/10717544.2021.2014603"]}}