{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chuang MA"],"funding":["Roche","National Health and Medical Research Council","Royal Australasian College of Physicians"],"pagination":["100933"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8728427"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38"],"pubmed_abstract":["<h4>Background</h4>To understand the economic impact of an accelerated 0/1-hour high-sensitivity troponin-T (hs-cTnT) protocol.<h4>Objective</h4>To conduct a patient-level economic analysis of the RAPID-TnT randomised trial in patients presenting with suspected acute coronary syndrome (ACS).<h4>Methods</h4>An economic evaluation was conducted with 3265 patients randomised to either the 0/1-hour hs-cTnT protocol (n = 1634) or the conventional 0/3-hour standard-of-care protocol (n = 1631) with costs reported in Australian dollars. The primary clinical outcome was all-cause mortality or new/recurrent myocardial infarction.<h4>Results</h4>Over 12-months, mean per patient costs were numerically higher in the 0/1-hour arm compared to the conventional 0/3-hour arm (by $472.49/patient, 95% confide"],"journal":["International journal of cardiology. Heart & vasculature"],"pubmed_title":["Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: An analysis of the RAPID-TnT trial."],"pmcid":["PMC8728427"],"funding_grant_id":["GNT1124471"],"pubmed_authors":["Blyth A","Quinn S","Karnon J","Nguyen MT","Chew DP","Horsfall M","French JK","Briffa T","Chuang MA","Lambrakis K","Seshadri A","Cullen LA","Gnanamanickam ES"],"additional_accession":[]},"is_claimable":false,"name":"Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: An analysis of the RAPID-TnT trial.","description":"<h4>Background</h4>To understand the economic impact of an accelerated 0/1-hour high-sensitivity troponin-T (hs-cTnT) protocol.<h4>Objective</h4>To conduct a patient-level economic analysis of the RAPID-TnT randomised trial in patients presenting with suspected acute coronary syndrome (ACS).<h4>Methods</h4>An economic evaluation was conducted with 3265 patients randomised to either the 0/1-hour hs-cTnT protocol (n = 1634) or the conventional 0/3-hour standard-of-care protocol (n = 1631) with costs reported in Australian dollars. The primary clinical outcome was all-cause mortality or new/recurrent myocardial infarction.<h4>Results</h4>Over 12-months, mean per patient costs were numerically higher in the 0/1-hour arm compared to the conventional 0/3-hour arm (by $472.49/patient, 95% confide","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-05T10:53:49.929Z","creation":"2022-02-11T15:19:58.078Z"},"accession":"S-EPMC8728427","cross_references":{"pubmed":["35024428"],"doi":["10.1016/j.ijcha.2021.100933"]}}