biostudies-literatureChuang MARocheNational Health and Medical Research CouncilRoyal Australasian College of Physicians100933https://www.ebi.ac.uk/biostudies/studies/S-EPMC8728427biostudies-literatureUnknown38<h4>Background</h4>To understand the economic impact of an accelerated 0/1-hour high-sensitivity troponin-T (hs-cTnT) protocol.<h4>Objective</h4>To conduct a patient-level economic analysis of the RAPID-TnT randomised trial in patients presenting with suspected acute coronary syndrome (ACS).<h4>Methods</h4>An economic evaluation was conducted with 3265 patients randomised to either the 0/1-hour hs-cTnT protocol (n = 1634) or the conventional 0/3-hour standard-of-care protocol (n = 1631) with costs reported in Australian dollars. The primary clinical outcome was all-cause mortality or new/recurrent myocardial infarction.<h4>Results</h4>Over 12-months, mean per patient costs were numerically higher in the 0/1-hour arm compared to the conventional 0/3-hour arm (by $472.49/patient, 95% confideInternational journal of cardiology. Heart & vasculatureCost effectiveness of a 1-hour high-sensitivity troponin-T protocol: An analysis of the RAPID-TnT trial.PMC8728427GNT1124471Blyth AQuinn SKarnon JNguyen MTChew DPHorsfall MFrench JKBriffa TChuang MALambrakis KSeshadri ACullen LAGnanamanickam ESfalseCost effectiveness of a 1-hour high-sensitivity troponin-T protocol: An analysis of the RAPID-TnT trial.<h4>Background</h4>To understand the economic impact of an accelerated 0/1-hour high-sensitivity troponin-T (hs-cTnT) protocol.<h4>Objective</h4>To conduct a patient-level economic analysis of the RAPID-TnT randomised trial in patients presenting with suspected acute coronary syndrome (ACS).<h4>Methods</h4>An economic evaluation was conducted with 3265 patients randomised to either the 0/1-hour hs-cTnT protocol (n = 1634) or the conventional 0/3-hour standard-of-care protocol (n = 1631) with costs reported in Australian dollars. The primary clinical outcome was all-cause mortality or new/recurrent myocardial infarction.<h4>Results</h4>Over 12-months, mean per patient costs were numerically higher in the 0/1-hour arm compared to the conventional 0/3-hour arm (by $472.49/patient, 95% confide2022-01-01T00:00:00Z2022 Feb2025-04-05T10:53:49.929Z2022-02-11T15:19:58.078ZS-EPMC87284273502442810.1016/j.ijcha.2021.100933