{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(12)"],"submitter":["Zhu Y"],"pubmed_abstract":["<h4>Background</h4>A diversity of surgical strategies are used to treat Marfan syndrome patients with aortic disease. We sought to evaluate the long-term efficiency of aortic root replacement (ARR) for patients with Marfan syndrome.<h4>Methods</h4>Data were collected from 131 patients with Marfan syndrome and aortic disease who underwent ARR in our center. We retrospectively analyzed the long-term outcomes of these patients, among whom 68 had been diagnosed with aortic aneurysm (AA) and had undergone ARR. The remaining 63 patients had aortic dissection (AD); of these, 35 underwent ARR for limited ascending AD, while the others underwent ARR and total arch replacement combined with frozen elephant trunk (FET). Risk factors for survival and reoperation were identified.<h4>Results</h4>The ope"],"journal":["Journal of thoracic disease"],"pagination":["6779-6789"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8743404"],"repository":["biostudies-literature"],"pubmed_title":["Long-term outcomes after aortic root replacement for patients with Marfan syndrome."],"pmcid":["PMC8743404"],"pubmed_authors":["Ma R","Zhu Y","Xiao Y","Wang Y","Jian Z"],"additional_accession":[]},"is_claimable":false,"name":"Long-term outcomes after aortic root replacement for patients with Marfan syndrome.","description":"<h4>Background</h4>A diversity of surgical strategies are used to treat Marfan syndrome patients with aortic disease. We sought to evaluate the long-term efficiency of aortic root replacement (ARR) for patients with Marfan syndrome.<h4>Methods</h4>Data were collected from 131 patients with Marfan syndrome and aortic disease who underwent ARR in our center. We retrospectively analyzed the long-term outcomes of these patients, among whom 68 had been diagnosed with aortic aneurysm (AA) and had undergone ARR. The remaining 63 patients had aortic dissection (AD); of these, 35 underwent ARR for limited ascending AD, while the others underwent ARR and total arch replacement combined with frozen elephant trunk (FET). Risk factors for survival and reoperation were identified.<h4>Results</h4>The ope","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-19T20:34:06.678Z","creation":"2025-04-19T20:34:06.678Z"},"accession":"S-EPMC8743404","cross_references":{"pubmed":["35070362"],"doi":["10.21037/jtd-21-577"]}}