{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kleckner AS"],"funding":["Maryland Department of Health's Cigarette Restitution Fund Program","American Cancer Society","Maryland Department of Health's Cigarette Restitution Fund Program","National Cancer Institute","NCI NIH HHS"],"pagination":["184"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8747418"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["Cancer-related fatigue is a prevalent and debilitating condition that persists for years into survivorship. Studies evaluating both fish oil supplementation on fatigue and associations between fish oil consumption and fatigue have shown mixed effects; it is unknown what factors contribute to these differential effects. Herein, we investigate whether the nutritional status of cancer survivors was associated with serum omega-3 concentration or change in serum omega-3s throughout a fish oil supplementation study, and then if any of these factors were associated with fatigue. Breast cancer survivors 4-36 months post-treatment with moderate-severe fatigue were randomized to take 6 g fish oil, 6 g soybean oil, or 3 g of each daily for 6 weeks. Baseline nutritional status was calculated using the"],"journal":["Nutrients"],"pubmed_title":["Nutritional Status Predicts Fatty Acid Uptake from Fish and Soybean Oil Supplements for Treatment of Cancer-Related Fatigue: Results from a Phase II Nationwide Study."],"pmcid":["PMC8747418"],"funding_grant_id":["R03CA175599","K07CA221931","N/A","CRP-19-175-06-COUN","UG1CA189961","T32CA102618","P30CA134274"],"pubmed_authors":["Kleckner AS","Parker EA","Ontko M","Demark-Wahnefried W","Janelsins MC","Kleckner IR","Belcher EK","Padula GDA","Peppone LJ","Mustian KM","Culakova E"],"additional_accession":[]},"is_claimable":false,"name":"Nutritional Status Predicts Fatty Acid Uptake from Fish and Soybean Oil Supplements for Treatment of Cancer-Related Fatigue: Results from a Phase II Nationwide Study.","description":"Cancer-related fatigue is a prevalent and debilitating condition that persists for years into survivorship. Studies evaluating both fish oil supplementation on fatigue and associations between fish oil consumption and fatigue have shown mixed effects; it is unknown what factors contribute to these differential effects. Herein, we investigate whether the nutritional status of cancer survivors was associated with serum omega-3 concentration or change in serum omega-3s throughout a fish oil supplementation study, and then if any of these factors were associated with fatigue. Breast cancer survivors 4-36 months post-treatment with moderate-severe fatigue were randomized to take 6 g fish oil, 6 g soybean oil, or 3 g of each daily for 6 weeks. Baseline nutritional status was calculated using the","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2026-04-08T10:07:42.304Z","creation":"2022-02-11T16:12:40.148Z"},"accession":"S-EPMC8747418","cross_references":{"pubmed":["35011059"],"doi":["10.3390/nu14010184"]}}