{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Steinberg BA"],"funding":["NHLBI NIH HHS","National Heart, Lung, and Blood Institute","National Institutes of Health"],"pagination":["13-20"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8748275"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["28(1)"],"pubmed_abstract":["<h4>Background</h4>Atrial fibrillation (AF) frequently complicates heart failure (HF), and each is associated with lower overall health-related quality of life. We aimed to quantify the incremental burden of AF on the health-related quality of life of patients with HF in clinical practice.<h4>Methods and results</h4>We used data from the Utah mEVAL program to analyze patient-reported outcomes (PROs) among patients with HF with and without AF. The primary outcome was the HF-specific Kansas City Cardiomyopathy Questionnaire, with generic PROs as secondary outcomes. Among 1707 patients with HF, 36% had AF (n = 616). Those with HF and AF were older (mean age 69 years vs 58 years, P < .001), more likely to have prior stroke (29% vs 17%, P < .001) and ischemic cardiomyopathy (28% vs 23%, P = .01"],"journal":["Journal of cardiac failure"],"pubmed_title":["Quantifying the Impact of Atrial Fibrillation on Heart Failure-Related Patient-Reported Outcomes in the Utah mEVAL Program."],"pmcid":["PMC8748275"],"funding_grant_id":["K23HL143156","K23 HL143156"],"pubmed_authors":["Greene T","Siu A","Bunch TJ","Steinberg BA","Zhang M","Lyons A","Bensch J","Hess R","Wohlfahrt P","Fang JC","Piccini JP","Spertus JA","Stehlik J"],"additional_accession":[]},"is_claimable":false,"name":"Quantifying the Impact of Atrial Fibrillation on Heart Failure-Related Patient-Reported Outcomes in the Utah mEVAL Program.","description":"<h4>Background</h4>Atrial fibrillation (AF) frequently complicates heart failure (HF), and each is associated with lower overall health-related quality of life. We aimed to quantify the incremental burden of AF on the health-related quality of life of patients with HF in clinical practice.<h4>Methods and results</h4>We used data from the Utah mEVAL program to analyze patient-reported outcomes (PROs) among patients with HF with and without AF. The primary outcome was the HF-specific Kansas City Cardiomyopathy Questionnaire, with generic PROs as secondary outcomes. Among 1707 patients with HF, 36% had AF (n = 616). Those with HF and AF were older (mean age 69 years vs 58 years, P < .001), more likely to have prior stroke (29% vs 17%, P < .001) and ischemic cardiomyopathy (28% vs 23%, P = .01","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-19T18:07:34.065Z","creation":"2025-04-19T18:07:34.065Z"},"accession":"S-EPMC8748275","cross_references":{"pubmed":["34324927"],"doi":["10.1016/j.cardfail.2021.07.009"]}}