biostudies-literatureUnknown59(2)Garland K<h4>Objective</h4>To perform a systematic review of the literature to identify the long-term effects of presurgical orthopedic (PSO) device use on patient outcomes.<h4>Design</h4>A comprehensive literature review of Embase and Ovid databases was performed to identify all English-language publications related to unilateral cleft lip and palate, presurgical devices, and patient outcomes. Studies were excluded if they did not report patient outcomes beyond 2 years of age, did not describe the use of a PSO device, were case reports (n < 10), or were purely descriptive studies.<h4>Main outcome measures</h4>Reported patient outcomes following the use of PSO devices.<h4>Results</h4>Following a review of all articles by 2 independent reviews, 30 articles were selected for inclusion. Overall, thereThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association156-165https://www.ebi.ac.uk/biostudies/studies/S-EPMC8750140biostudies-literatureSystematic Review of the Long-Term Effects of Presurgical Orthopedic Devices on Patient Outcomes.PMC8750140Dubois LGarland KMatic DMcNeely BfalseSystematic Review of the Long-Term Effects of Presurgical Orthopedic Devices on Patient Outcomes.<h4>Objective</h4>To perform a systematic review of the literature to identify the long-term effects of presurgical orthopedic (PSO) device use on patient outcomes.<h4>Design</h4>A comprehensive literature review of Embase and Ovid databases was performed to identify all English-language publications related to unilateral cleft lip and palate, presurgical devices, and patient outcomes. Studies were excluded if they did not report patient outcomes beyond 2 years of age, did not describe the use of a PSO device, were case reports (n < 10), or were purely descriptive studies.<h4>Main outcome measures</h4>Reported patient outcomes following the use of PSO devices.<h4>Results</h4>Following a review of all articles by 2 independent reviews, 30 articles were selected for inclusion. Overall, there2022-01-01T00:00:00Z2022 Feb2025-06-01T12:06:26.261Z2025-06-01T12:06:26.261ZS-EPMC87501403367805110.1177/1055665621998176