biostudies-literatureMolina Garcia ABill &amp; Melinda Gates FoundationChildren&apos;s Investment Fund FoundationThe ELMA FoundationThe John D and Catherine T MacArthur FoundationThe Lemelson FoundationMedical Research CouncilRice UniversityAustralian Commonwealth GovernmentNational Institute for Health Research (NIHR)Ting Tsung and Wei Fong Chao Family FoundationCaixabank SA101259https://www.ebi.ac.uk/biostudies/studies/S-EPMC8760419biostudies-literatureUnknown44<h4>Background</h4>Health care-associated infections (HCAI) in neonatal units in low- and middle-income countries (LMIC) are a major cause of mortality. This scoping review aimed to synthesise published literature on infection prevention and care bundles addressing neonatal HCAI in LMICs and to construct a Classification Framework for their components (elements).<h4>Methods</h4>Five electronic databases were searched between January 2001 and July 2020. A mixed-methods approach was applied: qualitative content analysis was used to build a classification framework to categorise bundle elements and the contents of the classification groups were then described quantitatively.<h4>Findings</h4>3619 records were screened, with 44 eligible studies identified. The bundle element Classification FramEClinicalMedicineInfection prevention and care bundles addressing health care-associated infections in neonatal care in low-middle income countries: a scoping review.PMC8760419MR/S004971/1Molina Garcia AMolyneux EMIrimu GKawaza KEzeaka VCwith the NEST360 Infection Prevention, Detection and Care Collaborative GroupLawn JEChiume MCross JHOkomo USpotswood NEFitchett EJASalim NfalseInfection prevention and care bundles addressing health care-associated infections in neonatal care in low-middle income countries: a scoping review.<h4>Background</h4>Health care-associated infections (HCAI) in neonatal units in low- and middle-income countries (LMIC) are a major cause of mortality. This scoping review aimed to synthesise published literature on infection prevention and care bundles addressing neonatal HCAI in LMICs and to construct a Classification Framework for their components (elements).<h4>Methods</h4>Five electronic databases were searched between January 2001 and July 2020. A mixed-methods approach was applied: qualitative content analysis was used to build a classification framework to categorise bundle elements and the contents of the classification groups were then described quantitatively.<h4>Findings</h4>3619 records were screened, with 44 eligible studies identified. The bundle element Classification Fram2022-01-01T00:00:00Z2022 Feb2026-06-03T10:16:32.604Z2025-04-05T12:49:20.681ZS-EPMC87604193505961410.1016/j.eclinm.2021.101259