{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11"],"submitter":["Safi S"],"pubmed_abstract":["Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (<i>KLF9</i>) was also determined in order to better understand its function, and a signaling pathway was constructed to identity its upstream and downstream targets. In the current study, the co-expressions of tumor protein D52 (<i>TPD52</i>), <i>KLF9</i>, microRNA 223 (miR-223), and protein kinase C epsilon (<i>PKCϵ</i>) were evaluated in cervical cancer patients and a possible relation with disease outcome was revealed. The expressions of <i>TPD52</i>, <i>KLF9</i>, miR-223, and <i>PKCϵ</i> were studied in the blood of 100 cervical cancer patients and 100 healthy controls using real-time PCR. The 3D structur"],"journal":["Frontiers in oncology"],"pagination":["797007"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8761731"],"repository":["biostudies-literature"],"pubmed_title":["Predicting 3D Structure, Cross Talks, and Prognostic Significance of <i>KLF9</i> in Cervical Cancer."],"pmcid":["PMC8761731"],"pubmed_authors":["Badshah Y","Abulmeaty M","Razak S","Alruwaili NW","Almajwal A","Afsar T","Khan K","Shabbir M","Dilshad E","Safi S","Zahra K","Al-Disi D"],"additional_accession":[]},"is_claimable":false,"name":"Predicting 3D Structure, Cross Talks, and Prognostic Significance of <i>KLF9</i> in Cervical Cancer.","description":"Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (<i>KLF9</i>) was also determined in order to better understand its function, and a signaling pathway was constructed to identity its upstream and downstream targets. In the current study, the co-expressions of tumor protein D52 (<i>TPD52</i>), <i>KLF9</i>, microRNA 223 (miR-223), and protein kinase C epsilon (<i>PKCϵ</i>) were evaluated in cervical cancer patients and a possible relation with disease outcome was revealed. The expressions of <i>TPD52</i>, <i>KLF9</i>, miR-223, and <i>PKCϵ</i> were studied in the blood of 100 cervical cancer patients and 100 healthy controls using real-time PCR. The 3D structur","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-05-18T11:36:41.859Z","creation":"2022-02-11T16:12:11.35Z"},"accession":"S-EPMC8761731","cross_references":{"pubmed":["35047407"],"doi":["10.3389/fonc.2021.797007"]}}