biostudies-literatureUnknown11Safi SOur study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (<i>KLF9</i>) was also determined in order to better understand its function, and a signaling pathway was constructed to identity its upstream and downstream targets. In the current study, the co-expressions of tumor protein D52 (<i>TPD52</i>), <i>KLF9</i>, microRNA 223 (miR-223), and protein kinase C epsilon (<i>PKCϵ</i>) were evaluated in cervical cancer patients and a possible relation with disease outcome was revealed. The expressions of <i>TPD52</i>, <i>KLF9</i>, miR-223, and <i>PKCϵ</i> were studied in the blood of 100 cervical cancer patients and 100 healthy controls using real-time PCR. The 3D structurFrontiers in oncology797007https://www.ebi.ac.uk/biostudies/studies/S-EPMC8761731biostudies-literaturePredicting 3D Structure, Cross Talks, and Prognostic Significance of <i>KLF9</i> in Cervical Cancer.PMC8761731Badshah YAbulmeaty MRazak SAlruwaili NWAlmajwal AAfsar TKhan KShabbir MDilshad ESafi SZahra KAl-Disi DfalsePredicting 3D Structure, Cross Talks, and Prognostic Significance of <i>KLF9</i> in Cervical Cancer.Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (<i>KLF9</i>) was also determined in order to better understand its function, and a signaling pathway was constructed to identity its upstream and downstream targets. In the current study, the co-expressions of tumor protein D52 (<i>TPD52</i>), <i>KLF9</i>, microRNA 223 (miR-223), and protein kinase C epsilon (<i>PKCϵ</i>) were evaluated in cervical cancer patients and a possible relation with disease outcome was revealed. The expressions of <i>TPD52</i>, <i>KLF9</i>, miR-223, and <i>PKCϵ</i> were studied in the blood of 100 cervical cancer patients and 100 healthy controls using real-time PCR. The 3D structur2021-01-01T00:00:00Z20212025-05-18T11:36:41.859Z2022-02-11T16:12:11.35ZS-EPMC87617313504740710.3389/fonc.2021.797007