{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gurgel M"],"funding":["Coordination for the Improvement of Higher Education Personnel","NIDCR NIH HHS","National Institute of Dental and Craniofacial Research","National Institute of Dental and Craniofacial Research (US)","Department of Radiology and Biomedical Imaging, University of California, San Francisco"],"pagination":["875-887"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8761785"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(1)"],"pubmed_abstract":["<h4>Objectives</h4>This study aims to assess craniofacial dimensions in obstructive sleep apnea (OSA) patients treated with a mandibular advancement device (MAD) and to identify anatomic influences on OSA severity and MAD therapy outcomes.<h4>Materials and methods</h4>Twenty patients with OSA were prospectively treated with MAD. Clinical, cone-beam computed tomography, and polysomnography exams were performed before treatment and 4-6 months after achieving the MAD therapeutic position. Polysomnographic exams and three-dimensional maxillary, mandibular, and upper airway (UA) measurements were evaluated. Pearson's correlation and t-tests were applied.<h4>Results</h4>Before MAD treatment, the transverse width measured at the frontomaxillary suture and the angle between the mandibular ramus an"],"journal":["Clinical oral investigations"],"pubmed_title":["Three-dimensional craniofacial characteristics associated with obstructive sleep apnea severity and treatment outcomes."],"pmcid":["PMC8761785"],"funding_grant_id":["R01DE024450","R01 DE024450"],"pubmed_authors":["Ruellas A","Bittencourt L","Pereira R","Cunali P","Gurgel M","Cevidanes L","Junior CC","Costa F","Bianchi J"],"additional_accession":[]},"is_claimable":false,"name":"Three-dimensional craniofacial characteristics associated with obstructive sleep apnea severity and treatment outcomes.","description":"<h4>Objectives</h4>This study aims to assess craniofacial dimensions in obstructive sleep apnea (OSA) patients treated with a mandibular advancement device (MAD) and to identify anatomic influences on OSA severity and MAD therapy outcomes.<h4>Materials and methods</h4>Twenty patients with OSA were prospectively treated with MAD. Clinical, cone-beam computed tomography, and polysomnography exams were performed before treatment and 4-6 months after achieving the MAD therapeutic position. Polysomnographic exams and three-dimensional maxillary, mandibular, and upper airway (UA) measurements were evaluated. Pearson's correlation and t-tests were applied.<h4>Results</h4>Before MAD treatment, the transverse width measured at the frontomaxillary suture and the angle between the mandibular ramus an","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-19T18:08:30.812Z","creation":"2025-04-19T18:08:30.812Z"},"accession":"S-EPMC8761785","cross_references":{"pubmed":["34273012"],"doi":["10.1007/s00784-021-04066-5"]}}