biostudies-literatureGidener TNIBIB NIH HHSNIDDK NIH HHSNational Institute of Diabetes and Digestive and Kidney DiseasesU.S. Department of DefenseNational Institute of Biomedical Imaging and Bioengineering379-390https://www.ebi.ac.uk/biostudies/studies/S-EPMC8766880biostudies-literatureUnknown75(2)<h4>Background and aims</h4>Although magnetic resonance elastography (MRE) has been well-established for detecting and staging liver fibrosis, its prognostic role in determining outcomes of chronic liver disease (CLD) is mostly unknown.<h4>Approach and results</h4>This retrospective study consisted of 1269 subjects who underwent MRE between 2007 and 2009 and followed up until death or last known clinical encounter or end of study period. Charts were reviewed for cirrhosis development, decompensation, and transplant or death. The cohort was split into baseline noncirrhosis (group 1), compensated cirrhosis (group 2), and decompensated cirrhosis (group 3). Cox-regression analysis with age, sex, splenomegaly, CLD etiology, Child-Pugh Score (CPS), Fibrosis-4 Index (FIB-4) score, and Model for EHepatology (Baltimore, Md.)Magnetic resonance elastography for prediction of long-term progression and outcome in chronic liver disease: A retrospective study.PMC8766880R37 EB001981R01 EB017197K23 DK115594EB017197W81XWH‐19‐1‐0583‐01EB001981R01 EB001981DK115594Gidener TDierkhising RAEhman RLAllen AMYin MVenkatesh SKfalseMagnetic resonance elastography for prediction of long-term progression and outcome in chronic liver disease: A retrospective study.<h4>Background and aims</h4>Although magnetic resonance elastography (MRE) has been well-established for detecting and staging liver fibrosis, its prognostic role in determining outcomes of chronic liver disease (CLD) is mostly unknown.<h4>Approach and results</h4>This retrospective study consisted of 1269 subjects who underwent MRE between 2007 and 2009 and followed up until death or last known clinical encounter or end of study period. Charts were reviewed for cirrhosis development, decompensation, and transplant or death. The cohort was split into baseline noncirrhosis (group 1), compensated cirrhosis (group 2), and decompensated cirrhosis (group 3). Cox-regression analysis with age, sex, splenomegaly, CLD etiology, Child-Pugh Score (CPS), Fibrosis-4 Index (FIB-4) score, and Model for E2022-01-01T00:00:00Z2022 Feb2025-04-19T17:57:17.849Z2025-04-19T17:57:17.849ZS-EPMC87668803451051310.1002/hep.32151