biostudies-literatureBrener MINHLBI NIH HHSe009101https://www.ebi.ac.uk/biostudies/studies/S-EPMC8766922biostudies-literatureUnknown15(1)Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and diastolic properties independent of loading conditions like volume status and afterload. While long-considered the gold-standard method for quantifying myocardial chamber performance, it was traditionally only performed in highly specialized research settings. With recent advances in catheter technology and more sophisticated approaches to analyze PV data, it is now more commonly used in a variety of clinical and research settings. Herein, we review the basic techniques for PV loop measurement, analysis, and interpretation with the aim of providing readers with a deeper understanding of the strengths and limitations of PV analysis. In the second half of the review, we detail key scenarios in which right Circulation. Heart failureInvasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations.PMC8766922T32 HL007343Tello KHiremath GNg VGTedford RJMasoumi AVan Mieghem NMKanwar MKHeerdt PMBurkhoff DBrener MICornwell WKSayer GTUriel NHsu SHahn RTBastos MBLurz PRommel KPKresoja KPSarraf MNagueh SFKodali SKKapur NKVan Den Enden AJMfalseInvasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations.Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and diastolic properties independent of loading conditions like volume status and afterload. While long-considered the gold-standard method for quantifying myocardial chamber performance, it was traditionally only performed in highly specialized research settings. With recent advances in catheter technology and more sophisticated approaches to analyze PV data, it is now more commonly used in a variety of clinical and research settings. Herein, we review the basic techniques for PV loop measurement, analysis, and interpretation with the aim of providing readers with a deeper understanding of the strengths and limitations of PV analysis. In the second half of the review, we detail key scenarios in which right 2022-01-01T00:00:00Z2022 Jan2025-04-21T15:24:25.591Z2025-04-21T15:24:25.591ZS-EPMC87669223496330810.1161/circheartfailure.121.00910110.1161/CIRCHEARTFAILURE.121.009101